Citation: Niema Benkhraba et al. Paragangliomas of Nasal Cavity: A Case Report. Sch J Med Case Rep, 2021 June 9(6): 673-675. 673 Scholars Journal of Medical Case Reports Abbreviated Key Title: Sch J Med Case Rep ISSN 2347-9507 (Print) | ISSN 2347-6559 (Online) Journal homepage: https://saspublishers.com Paragangliomas of Nasal Cavity: A Case Report Niema Benkhraba 1 , 3* , Mohamed Ali Gliti 1 , 3 , Ihssane Allouch 1 , 3 , Sophia Nitassi 2 , 3 , Bencheikh Razika 2 , 3 , Benbouzid Mohamed Anas 2 , 3 , Abdelilah Oujilal 2 , 3 , Leila Essakalli Houssyni 2 , 3 1 Resident physician in otorhinolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Ibn Sina University Hospital, Rabat, Morocco 2 Professor of otorhinolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Ibn Sina University Hospital, Rabat, Morocco 3 Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco DOI: 10.36347/sjmcr.2021.v09i06.015 | Received: 19.04.2021 | Accepted: 27.05.2021 | Published: 22.06.2021 *Corresponding author: Niema Benkhraba Abstract Case Report Paraganglioma is a rare neuroendocrine tumor. Nasal localization is very rare. Head and neck paragangliomas represent only 0.6% of head and neck tumors and 3% of all paragangliomas. The treatment is based on surgery. Radiotherapy is indicated if the surgery does not provide complete resection. We report the case of a 36-year-old patient who has had left nasal obstruction with epistaxis for 2 years. The CT scan shows a solid mass centered on the left nasal cavity, puffy, without signs of aggression, benign-looking. The patient underwent a complete endoscopic endonasal tumor removal after preoperative external carotid embolization. Pathological analysis with immunohistochemistry confirmed the diagnosis of paraganglioma. The follow-up to the treatment was favorable. Keywords: Paragangliomas, Nasal cavity, Surgery, Radiotherapy, Embolization. Copyright © 2021 The Author(s): This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY-NC 4.0) which permits unrestricted use, distribution, and reproduction in any medium for non-commercial use provided the original author and source are credited. INTRODUCTION Paraganglioma is a rare neuroendocrine tumor resulting from the migration of neural crest cells associated with the autonomic nervous system [10, 14]. The sanctuary sites for these tumors are the medullary portion of the adrenal gland (pheochromocytomas), intercarotid glomus, and jugulotympanic glomus [14]. Nasopharyngeal paraganglioma is one of the rare locations of paragangliomas of the head and neck which themselves represent only 3% of all paragangliomas [3]. The aim of this work is to report a rare localization of paragangliomas. CASE REPORT This is a 36-year-old patient, followed for hypothyroidism, who has presented for 2 years with progressive worsening left unilateral nasal obstruction, associated with epistaxis, clear and sometimes purulent anterior rhinorrhea. Without facial pain and without associated ophthalmological signs. Clinical examination found a deformation of the nasal pyramid, with the presence of a fleshy tumor bleeding on contact obstructing the entire left nasal cavity and exerting a mass effect on the contralateral nasal cavity, the nasal flow was abolished on the left side and very reduced on the right side (Figure 1). CT scan of the nasal cavity and cavum shows a lesional process centered on the left nasal cavity, dense, moderately enhanced and heterogeneous. This process blows the bony cortex of the jawbone downwards, the bony skeleton of the inferior turbinate, and the internal wall of the left maxillary sinus laterally. Forward, it fills the nostril. And back, it fills the choana and bombs in the nasopharyngeal lumen. With retentional sphenoidal and left maxillary sinusitis (Figure 2). An anatomopathological study of a biopsy of the tumor shows a morphological appearance suggesting a paraganglioma of the nasal cavities or an inverse papilloma. An immunohistochemical complement was done, returning in favor of a paraganglioma. The patient received preoperative embolization. A complete exeresis of the tumor of the left nasal cavity was performed by endonasal endoscopic approach (Figure 3). The definitive anatomopathological study concluded in a paraganglioma. The operative consequences were simple. The evolution was favorable with no signs of recurrence with a 1-year follow-up.