Vol.:(0123456789) 1 3
Eur J Nutr
DOI 10.1007/s00394-017-1402-6
ORIGINAL CONTRIBUTION
The relationship between carbohydrate quality and the prevalence
of metabolic syndrome: challenges of glycemic index and glycemic
load
Mariane de Mello Fontanelli
1
· Cristiane Hermes Sales
1
·
Antonio Augusto Ferreira Carioca
1
· Dirce Maria Marchioni
1
· Regina Mara Fisberg
1
Received: 12 November 2016 / Accepted: 10 February 2017
© Springer-Verlag Berlin Heidelberg 2017
and OR = 1.019 (95% CI 1.002–1.037), respectively. GL
was inversely associated with high blood pressure and this
association difered by age group (OR = 0.981; 95% CI
0.964–0.998). Foods that most contributed to dietary GI
and GL were sugar, white rice and French bread.
Conclusions Considering the high prevalence of low
HDL-c in the population of São Paulo, GI and GL may
contribute to the nutritional therapy of this dyslipidemia.
However, fndings should be treated with caution, consider-
ing several conficting results between studies.
Keywords Metabolic Syndrome · Glycemic Index ·
Glycemic Load · Cross-sectional studies · Prevalence
Introduction
The prevalence of metabolic syndrome (MetS) in the
world’s adult population is estimated to be between 20
and 25% [1]; however, data from studies involving Brazil-
ian citizens between 19 and 64 years suggest higher rates
(29.6%) [2]. In the United States of America (USA), the
prevalence of MetS was found to be 34.7% between 2011
and 2012, 18.3% in individuals between 20 and 39 years
and 46.7% between individuals with 60 or more years. Data
from the National Health and Nutrition Examination Sur-
vey (NHANES) point to an increase in the prevalence of
MetS, from 32.9% in 2003–2004 to 34.7% in 2011–2012.
However, these fgures have remained stable since 2007, a
fact that was attributed to the stabilization of obesity rates
in the country [3].
Overweight and obesity are responsible for 3.4 mil-
lion deaths per year and 93.6 million disability-adjusted
life years (DALYs) in 2010, with the highest prevalence
in North and South America (61%) [4]. In 2013, the
Abstract
Purpose To estimate the prevalence of metabolic syn-
drome (MetS) and its components in adults and older adults
residents of São Paulo, the association of MetS with the
glycemic index (GI) and glycemic load (GL) and the foods
that contribute to dietary GI and GL in this population.
Methods Data from 591 adults and older adults partici-
pants in the Health Survey of São Paulo were used. This
is a cross-sectional, population-based study with a complex
multistage sample design of residents in the urban area of
the municipality. Dietary consumption data, anthropomet-
ric measurements, blood pressure and blood samples were
collected. The associations between GI, GL and MetS and
its components were tested using logistic regression mod-
els, considering the sample design of the study.
Results The prevalence of MetS in the adult and older
adults residents of São Paulo was 30.3%. There was no
association between GI, GL and MetS. GI and GL were
positively associated with low high-density lipoprotein
cholesterol (HDL-c), OR = 1.113 (95% CI 1.007–1.230)
* Regina Mara Fisberg
rfsberg@usp.br
Mariane de Mello Fontanelli
marianefontanelli@gmail.com
Cristiane Hermes Sales
cristianehermes@yahoo.com.br
Antonio Augusto Ferreira Carioca
nutriaugusto@gmail.com
Dirce Maria Marchioni
marchioni@usp.br
1
Department of Nutrition, School of Public Health, University
of São Paulo, Avenida Dr. Arnaldo, 715, Cerqueira Cesar,
01246-904 Sao Paulo, SP, Brazil