Page 1/32 Positional transcriptomics shed light on site- speciｦc pathologies of the aorta Milagros Romay Department of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Feinberg School of Medicine Feiyang Ma University of California, Los Angeles https://orcid.org/0000-0002-6260-0787 Gloria Hernandez University of California, Los Angeles / Northwestern University https://orcid.org/0000-0003-2882-811X Marie Vandestienne Medical Intensive Care Unit, Hopital Saint-Antoine, Assistance Publique-Hopitaux de Paris, Sorbonne Universite Todd Kimball Molecular, Cellular and Integrative Physiology Interdepartmental Graduate Program, University of California, Los Angeles Michele Silvestro Division of Endovascular surgery, Department of Surgery, New York University Langone Health Tarik Hadi Division of Endovascular surgery, Department of Surgery, New York University Langone Health Andrew Reyes Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Margaret Ramirez Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Nathalie Bardin Aix-Marseille University, INSERM Marcel Blot-Chabaud Aix-Marseille University, INSERM Matteo Pellegrini Department of Molecular, Cell and Developmental Biology, and Institute for Genomics and Proteomics, University of California, Los Angeles https://orcid.org/0000-0001-9355-9564 Aurelie Leroyer Aix-Marseille University, INSERM Haｦd Ait-Oufella Inserm Bhama Ramkhelawon