Advances in Sexual Medicine, 2016, 6, 1-13 Published Online January 2016 in SciRes. http://www.scirp.org/journal/asm http://dx.doi.org/10.4236/asm.2016.61001 How to cite this paper: Dapaah, J.M., Appiah, S.C.Y., Amankwaa, A. and Ohene, L.R. (2016) Knowledge about Sexual and Reproductive Health Services and Practice of What Is Known among Ghanaian Youth, a Mixed Method Approach. Advances in Sexual Medicine, 6, 1-13. http://dx.doi.org/10.4236/asm.2016.61001 Knowledge about Sexual and Reproductive Health Services and Practice of What Is Known among Ghanaian Youth, a Mixed Method Approach Jonathan Mensah Dapaah 1 , Seth Christopher Yaw Appiah 1* , Afua Amankwaa 2 , Larbi Rita Ohene 3 1 Department of Sociology and Social Work, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana 2 Beijing Normal University, Beijing, China 3 Department of Theoretical and Applied Biology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana Received 26 October 2015; accepted 24 January 2016; published 27 January 2016 Copyright © 2016 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract Most young person will become sexually active before their 20 th birthday having to battle with early and unplanned pregnancies, unsafe abortions, maternal deaths and injuries. This study ex- amined young person’s sexual knowledge, attitudes and practices and their levels of utilization of sexual reproductive health. Our study progresses beyond current research of reporting only sex- ual behaviour among youth to have insight into sexual and reproductive health update drivers yielding new empirically robust results for the Ghanaian case for sexual and reproductive health service uptake. The descriptively cross sectional design was employed in sampling 170 youth (150 surveyed and 20 Interviewed) using the stratified sampling technique together with a purposive selection of one key informant. Test of significance and associations were performed with the Chi- square test. In all 45.2% (77/170) of youth (10 - 24) had had sexual experience in life time. In re- spect of in-school youth, 42% (63/150) had had sexual experience whiles 70% (14/20) out-of- school youth had had sexual intercourse in life time. A total of 28.8% (49/170) of all the youth had sexual intercourse in the last six months with only 40.1 (20/49) using condom for protection. Pa- rental discussion of contraceptive methods (29.3%) and sexual and romantic relationship (28.0%) was the least sexual and reproductive health area discussed among in-school youth. Youth know- ledge of the available sexual reproductive health service was statistically associated with repro- ductive health service utilization (X 2 = 0.00, P ≤ 0.05). A concerted effort is required from govern- * Corresponding author.