Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/ejh.13318 This article is protected by copyright. All rights reserved. DR. MARIE ROBIN (Orcid ID : 0000-0003-1388-9876) PROF. NICOLAUS KRÖGER (Orcid ID : 0000-0002-2961-4183) Article type : Original Article Allogeneic stem cell transplantation in patients with myelofibrosis harboring the MPL-mutation Daniele Mannina 1,2 , Nico Gagelmann 1 , Anita Badbaran 1 , Markus Ditschkowski 3 , Rashit Bogdanov 4 , Marie Robin 4 , Bruno Cassinat 4 , Michael Heuser 5 , Rabia Shahswar 5 , Felicitas Thol 5 , Dietrich Beelen 3 , Nicolaus Kröger 1 1 Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany 2 Department of Hematology and Bone Marrow Transplantation, San Raffaele Hospital, Milan, Italy 3 Department of Bone Marrow Transplantation, West German Cancer Center, University Hospital of Essen, Germany 4 Department of Hematology, Saint-Louis Hospital, APHP. Paris, France 5 Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany Short running title: MPL mutation and allo SCT in MF Keywords: Myelofibrosis with myeloid metaplasia, Transplantation, Bone marrow transplantation, Molecular biology of myelopoiesis Figure legend: Figure 1. Mutational status of primary and post-ET myelofibrosis harboring MPL mutation before the transplantation. The most frequent additional mutations involve TET2 gene (33%). The incidence of prognostic-relevant ASXL1 mutations among our patients is 22.2%. Figure 2. shows overall survival. Figure 3. shows relapse-free survival Correspondence: Prof.Dr. med. Nicolaus Kröger Department of Stem Cell Transplantation University Medical Center Hamburg-Eppendorf Martinistraße 52, D-20246 Hamburg Tel.: +49-40-7410-54851 Fax: +49-40-7410-53795 Email: nkroeger@uke.uni-hamburg.de