S- 1 - Supporting Information for : Understanding the fate of environmental chemicals inside living organisms: NMR based 13 C isotopic suppression selects only the molecule of interest within 13 C enriched organisms Daniel Lane, †⊥ Yalda Liaghati Mobarhan, † Ronald Soong, † Paris Ning, † Wolfgang Bermel, ‡ Maryam Tabatabaei Anaraki, † Bing Wu, † Hermann Heumann, § Marcel Gundy, § Holger Boenisch, § Tae-Yong Jeong, † Vera Kovacevic, †⊥ Myrna J. Simpson, †⊥ André J. Simpson,* ,†⊥ † Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON, Canada, M1C 1A4 ⊥ Department of Chemistry, University of Toronto, 80 St. George St., Toronto, ON, Canada, M5S 3H6 ‡ Bruker BioSpin GmbH. Silberstreifen 4 , 76287 Rheinstetten, Germany § Silantes GmbH, 80339 München, Germany Corresponding Author *(andre.simpson@utoronto.ca) Table of Contents Experimental……………………………………………………………………………… Pages S2 Factors impacting the limit of detection and quantification of 12 C metabolites...……Pages S2-4 1D X Filtering NMR Pulse Sequence……………………………………………………Pages S5-11 Figure S2……………………………………………………………………………………Page S12