Accepted Manuscript New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death Teresa L. Serafim, Filipa S. Carvalho, Telma C. Bernardo, Gonçalo C. Pereira, Edward Perkins, Jon Holy, Dmytro A. Krasutsky, Oksana N. Kolomitsyna, Pavel A. Krasutsky, Paulo J. Oliveira PII: S0968-0896(14)00590-2 DOI: http://dx.doi.org/10.1016/j.bmc.2014.08.013 Reference: BMC 11761 To appear in: Bioorganic & Medicinal Chemistry Received Date: 19 May 2014 Accepted Date: 12 August 2014 Please cite this article as: Serafim, T.L., Carvalho, F.S., Bernardo, T.C., Pereira, G.C., Perkins, E., Holy, J., Krasutsky, D.A., Kolomitsyna, O.N., Krasutsky, P.A., Oliveira, P.J., New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death, Bioorganic & Medicinal Chemistry (2014), doi: http://dx.doi.org/ 10.1016/j.bmc.2014.08.013 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.