_____________________________________________________________________________________________________ *Corresponding author: Email: saheedkakako@yahoo.com, saheedkakako@udusok.edu.ng; European Journal of Nutrition & Food Safety 10(1): 50-55, 2019; Article no.EJNFS.2019.067 ISSN: 2347-5641 Prevalence of Insulin Resistance among Cigarette Smokers in Sokoto Metropolis Saheed Ladipo Kakako 1* , Taofeeq Oduola 1 , Muhammad Kabiru Dallatu 1 , Hauwa Bako 2 , Chidi Ugwuoke 3 and Ali Isah Ali 1 1 Department of Chemical Pathology, School of Medical Laboratory Science, Usmanu Danfodiyo University, Sokoto, Nigeria. 2 Department of Medical Laboratory Science, Ahmadu Bello University, Zaria, Nigeria. 3 Bayero University, Kano, Nigeria. Authors’ contributions This work was carried out in collaboration among all authors. Author SLK designed the study, wrote the protocol, and wrote the first draft of the manuscript. Authors TO, MKD, HB, CU and AIA managed the analyses of the study and literature searches, Author AIA performed the statistical analysis. All authors read and approved the final manuscript. Article Information DOI: 10.9734/EJNFS/2019/v10i130096 Editor(s): (1) Dr. Joanna Magdalena Zarzynska, Department of Food Hygiene and Human Health Protection, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, Poland. Reviewers: (1) Mra Aye, Melaka Manipal Medical College, Malaysia. (2) D. Minik, Sree Sankara College, India. (3) Serkan Yilmaz, Faculty of Health Sciences, Ankara University, Turkey. Complete Peer review History: http://www.sdiarticle3.com/review-history/51130 Received 20 June 2019 Accepted 24 August 2019 Published 31 August 2019 ABSTRACT Introduction: Cigarette smoking (CS) is a well-known risk factor for the development of metabolic diseases, various forms of cancer as well as insulin resistance (IR). IR is considered as an underlying derangement which very commonly aggravates metabolic syndrome. Aim: This study assessed the prevalence of IR in cigarette smokers in Sokoto metropolis using selected surrogate markers. Methodology: This cross sectional study was conducted in Sokoto among 108 subjects. Fasting venous blood samples were collected for plasma glucose, triglycerides and insulin estimation. Plasma glucose and serum triglycerides were analysed using enzymatic methods while insulin was assayed using ELISA method. Homeostasis model of assessment-IR (HOMA-IR), Quantitative insulin sensitivity check index (QUICKI), Mc Auley (McA) and fasting IR index (FIRI) Original Research Article