International Journal of Research & Review (www.ijrrjournal.com) 517 Vol.6; Issue: 8; August 2019 International Journal of Research and Review www.ijrrjournal.com E-ISSN: 2349-9788; P-ISSN: 2454-2237 Review Article Alkaloids and Non Alkaloids of Tabernaemontana divaricata Ankita Kulshreshtha 1 , Jyoti Saxena 2 1 Central Laboratory, Madhya Pradesh Pollution Control Board, Paryavaran Parisar, E-5, Arera Colony, Bhopal, India, 462016. 2 Department of Chemistry, Institute for Excellence in Higher Education, Kaliyasot Dam, Kolar Road, Bhopal, India, 462016. Corresponding Author: Ankita Kulshreshtha ABSTRACT Tabernaemontana divaricata is a garden plant which commonly known as Chandani, has been used as a traditional medicine with many pharmacological properties. Plants produce a lot of antioxidants to control the oxidative stress caused by sunbeams and oxygen, they can represent a source of new compounds with antioxidant activity. The beneficial properties of T. divaricata are antioxidant, anti- infection, anti-tumour action, analgesia and the enhancement of cholinergic activity in both peripheral and central nervous systems. In traditional medicine Tabernaemontana divaricata is used to treat various diseases like epilepsy, abdominal tumours, eye infections, fractures, fever, headache, inflammation, mania, oedema, leprosy, diarrhea. Many primary and secondary metabolites are present in the different parts of Tabernaemontana divaricata .The review reveals that alkaloids and non alkaloids present in the extract of parts of Tabernaemontana divaricata which can be applicable in various research applications. Total 66 alkaloids isolated and identified from T. divaricata. 34, Non- alkaloids including the enzymes, pyrolytic oil, hydrocarbons, terpenoid and phenolic acids are also listed in this review. Keywords: Tabernaemontana divaricata, Alkaloids, Non alkaloids INTRODUCTION Tabernaemontana divaricata is commonly known as Chandani from the family Apocynaceae. The plant is an evergreen shrub growing to a maximum height of six feet and found in all parts of the India. Normally a Plant produces various metabolic products for their growth and development. The components which are essential for the growth and survival for the producer plant are known as primary metabolites. Secondary metabolites are plant substances which are derived biosynthetically from primary metabolites. Flavanoids, alkaloids, terpenoids, phenols, tannins, saponins, steroids etc belong to this class. The presence of phenolic group imparts anti oxidant activity to flavonoids, phenols and tannins. Anti oxidant substances can block the action of free radicals which are responsible for the pathogenesis of various diseases. [1] This species has been extensively investigated and a number of chemical constituents such as alkaloids, triterpenoids, steroids, flavonoids, phenyl propanoids and phenolic acids were isolated from leaves, roots and stems of the plant. [2-10] Plants produce a lot of antioxidants to control the oxidative stress caused by sunbeams and oxygen, they can represent a source of new compounds with antioxidant activity. Free radicals are atoms or groups of atoms with an odd number of electrons and can be formed when oxygen interacts with certain molecules. Once highly reactive free