Int.J.Curr.Microbiol.App.Sci (2018) 7(11): 2720-2724 2720 Original Research Article https://doi.org/10.20546/ijcmas.2018.711.311 Anti Helminthis Activity of Alangium salviifolium against Pheretima posthumous K.P. Kochuthressia* Department of Botany, Carmel College, Mala (P.O), Thrissur – 680732, Kerala, India *Corresponding author ABSTRACT Introduction Despite of some biological advantages in the field of agriculture Helminthis are known for its expanded infection and disease spreading abilities. Therefore, it is crucial to improve efficient control agents against them (Cabardo and Portugaliza, 2017). Trematodes, the causal agents of schistosomiasis an important parasites of economic and public health implications. Schistosomiasis affects over 240 million people worldwide, with up to 700 million individuals living at risk of infection (Cala et al., 2012). The disease caused up to 250,000 deaths per year in the last decade (Kumarasingha et al., 2016). Similarly, Helminthis infection causes huge revenue in agro farming. There have been several synthetic chemical compounds and nanoparticles proven their anti helminthis activity. However, it is also observed that these compounds are mostly toxic to the environment. In this juncture it is essential to develop suitable ethnobotanical agents against this threat (Khan et al., 2018). Alangium salvifolium Wang. belongs to the family Alangiaceae and is commonly known as sage leaved Alangium. It is a well-known traditionally used medicinal plant in India and it is also one of the most versatile medicinal plant having a wide spectrum of biological International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 7 Number 11 (2018) Journal homepage: http://www.ijcmas.com The present study was intended to delineate the Anti Helminthis activity of Ankolam leaf extract. The crude extract was obtained by the employment of Soxhlet extraction method. The extract was used to screen the antagonistic activity in vitro by taking Pheretima posthumous as the study subject. B y the employment of molecular sequencing the identity of plant was confirmed as Alangium salviifolium. The results obtained proved the capability of extract to down regulate the biological activities of subject. Mortality was induced by varying concentrations (100-1000 ppm/ml). Interestingly the antagonistic activity was in direct proportional with the extract administrated. The analysis of phyto- constituents revealed that the extract is composed of polyphenols, Saponins, Flavonoids etc. Therefore, it is assumed that the biological activities are complimented by the phyto- components. The results obtained from the current studies can be further exploited in the field pharmaceuticals. Keywords Alangium salviifolium, Anti helminthis activity, Pheretima posthumous Accepted: 22 October 2018 Available Online: 10 November 2018 Article Info