© 2019 JETIR March 2019, Volume 6, Issue 3 www.jetir.org (ISSN-2349-5162) JETIREO06143 Journal of Emerging Technologies and Innovative Research (JETIR) www.jetir.org 628 A Review Paper on Role of Nanobiotechnology in Drug Discovery Sunita Bishnoi Department of Bio Technology Vivekananda Global University, Jaipur Email ID: bishnoi.sunita@vgu.ac.in ABSTRACT: In a variety of areas of the field of life science and biotechnology, nano-biotechnology has already tested its magnitude. It is no longer hyperbole to suggest that the nano-scale approach will potentially carry the relevant science sector to the next stage in the future. There are technological challenges, because, despite the fact that scientists give their greatness to solve such problems. This chapter has already explored the applications of nanobiotechnology. Innovative improvements to such applications are really correlated with future prospects. This technology, despite some impedance, offers giant hope for the future. In various kinds of biomedical applications, such as drug shipping, gene therapy, biosensors, biomarkers and molecular imaging, it plays the most important role. Moreover, it leads to advances in this area. Innovation of the early analysis method and cure with target-specific remedy therapy will be the fundamental research goal of this discipline. While there may be some safety issues regarding the in vivo use of nanoparticles, research is in the region to determine the type and degree of adverse effects. KEYWORDS: Molecular, Nanobiotechnology, Nano, Research, Science. INTRODUCTION The enhancement of the diagnostic process, the development of optimized drug loaded formulation and the integration of optimized formulation into the appropriate delivery system in terms of the role of nanotechnology in drug discovery and development require effective treatment for disease. Researchers have been challenged to increase analytical capability with enhanced data quality, consuming less sample volume for cell and tissue library storage and screening at the molecular level. The revolutionary format of nanotechnology provides technological advancement in the current scenario, overcoming the initial challenges of inaccurate results, consuming high samples and various other problems[1]. Figure 1: Illustrates the advantages of the nanobiotechnology[2]. DISCUSSION If we consider the two main capabilities of nanobiotechnology in trendy terms, first is imaging and diagnostics (quantum dots) and second is proteomics. In particular, nucleic acids and proteins are examined and detected in proteomics[3]. For the treatment of cancer, the Thermal Sensitive drug delivery system has now been created.