European Journal of Radiology 82 (2013) 1410–1415 Contents lists available at SciVerse ScienceDirect European Journal of Radiology journa l ho me p age: www.elsevier.com/locate/ejrad Revaluation of breast cytology with pathologist on-site of lesions with suspicious sonographic features Emanuela Capalbo a,∗,1,2 , Farideh Sajadidehkordi a,3 , Claudio Colombi b,4 , Vladimira Ticha b,5 , Angela Moretti b,6 , Michela Peli a,7 , Maria Cosentino a,8 , Maria Lovisatti a,9 , Elisabetta Berti c,10 , Maurizio Cariati b,11 a Scuola di Specializzazione di Radiologia Diagnostica ed Interventistica, Università degli Studi di Milano Via Di Rudinì, Milano, 20142 Italy b Dipartimento di Scienze Diagnostiche, UOC di Radiologia Diagnostica ed Interventistica, A.O San Carlo Borromeo. Via Pio II, 3, 20153 Milano, Italy c Dipartimento di Scienze Diagnostiche, UOC di Anatomia Patologica, A.O San Carlo Borromeo. Via Pio II, 3, Milano 20153, Italy a r t i c l e i n f o Article history: Received 12 December 2011 Received in revised form 14 December 2012 Accepted 4 March 2013 Keywords: Breast cancer Cytology Ultrasound FNAC a b s t r a c t Objective: Evaluating correlation estimation between diagnostic ultrasound (U.S.) of breast lesions and fine needle aspiration cytology (FNAC), and the correlation between cytology and histology (I) of these lesions undergo surgery. Materials and methods: In 2010 we performed 1589 ultrasound breast. We identified 210 suspicious lesions to be subjected to FNAC, which was performed with pathologist on site, and extemporaneous analysis of the sample to assess their appropriateness. We classified the lesions in 5 ultrasound (U) classes according to the criteria defined by Echographic BIRADS Lexicon. The results of cytology were classified in 5 classes (C) according to the guidelines of F.O.N.Ca.M. Then we evaluated the diagnostic correlation between U.S. and FNAC, and between FNAC and Histology. Results: The distribution of lesions in U classes was: 57U2, 55U3, 36U4 and 62U5. The diagnostic con- cordance between U and FNAC was 96.7%, with a sensitivity of 98%, specificity 93%, negative and positive predictive value respectively of 94.9% and 97.3%, and diagnostic accuracy of 96.6%. The 98 patients with C4-C5 lesions were subjected to surgery and the histology confirmed high-grade malignancy of lesions with a concordance of 99.7%. Conclusions: Having achieved high diagnostic concordance between U and FNAC, and then between FNAC and histology, we may say that the FNAC, less invasive and traumatic for the patient than needle biopsy (CB), may be still a valid method when performed with pathologist on-site to assess the adequacy of the sample taken. © 2013 Elsevier Ireland Ltd. All rights reserved. ∗ Corresponding author. Tel.: +39 320/4031233; fax: +39 02/40222465. E-mail addresses: emanuelacapalbo@tiscalinet.it (E. Capalbo), faridehit@yahoo.it (F. Sajadidehkordi), info.radiologia@sancarlo.mi.it (C. Colombi), info.radiologia@sancarlo.mi.it (V. Ticha), info.radiologia@sancarlo.mi.it (A. Moretti), peli.michela@gmail.com (M. Peli), maria-cosentino@tiscali.it (M. Cosentino), marialovisatti@hotmail.com (M. Lovisatti), eliberti@hotmail.it (E. Berti), info.radiologia@sancarlo.mi.it (M. Cariati). 1 Scuola di Specializzazione di Radiologia Diagnostica ed Interventistica, Università degli Studi di Milano. Via Di Rudinì, Milano, 20142 Italy. 2 Dipartimento di Scienze Diagnostiche, UOC di Radiologia Diagnostica ed Interventistica, A.O San Carlo Borromeo. Via Pio II, 3, 20153 Milano. 3 Tel.: +39 02/40222465; fax: +39 02/40222465. 4 Tel.: +39 02/40222465; fax: +39 02/40222465. 5 Tel.: +39 02/40222465; fax: +39 02/40222465. 6 Tel.: +39 02/40222465; fax: +39 02/40222465. 7 Tel.: +39 02/40222465; fax: +39 02/40222465. 8 Tel.: +39 02/40222465; fax: +39 02/40222465. 9 Tel.: +39 02/40222465; fax: +39 02/40222465. 10 Tel.: +39 02/40222465; fax: +39 02/40222465. 11 Tel.: +39 02/40222465; fax: +39 02/40222465. 0720-048X/$ – see front matter © 2013 Elsevier Ireland Ltd. All rights reserved. http://dx.doi.org/10.1016/j.ejrad.2013.03.004