1 3
Int J Clin Oncol
DOI 10.1007/s10147-017-1148-4
ORIGINAL ARTICLE
The rate of facial nerve dysfunction and time to recovery
after intraparotid and extraparotid facial nerve exposure
and protection in head and neck cutaneous tumor surgery
Yasuhiro Nakamura
1
· Yukiko Teramoto
1
· Yuri Asami
1
· Taichi Imamura
1
·
Sayuri Sato
1
· Ryota Tanaka
2
· Hiroshi Maruyama
2
· Yoshiyuki Nakamura
2
·
Yasuhiro Fujisawa
2
· Manabu Fujimoto
2
· Akifumi Yamamoto
1
Received: 21 February 2017 / Accepted: 31 May 2017
© Japan Society of Clinical Oncology 2017
intraparotid rates of paresis were 48% (11/23 branches) and
21.1% (4/19 branches), respectively, P = 0.139; and the
average recovery periods were 10.3 and 9.3 weeks, respec-
tively, P = 0.64.
Conclusions The functional outcome, regardless of the
different sites of facial nerve exposure, was almost always
either complete facial nerve sparing or transient dysfunc-
tion that resolved within 6 months.
Keywords Skin cancer · Melanoma · Squamous cell
carcinoma · Facial nerve · Sentinel lymph node biopsy ·
Neck dissection
Introduction
The head and neck account for only 9% of the total body
surface area, but 80% of all skin cancers occur in these
regions [1], most likely because of their greater exposure to
the sun. Despite the increasing incidence of head and neck
skin cancer, the prognosis is generally excellent. How-
ever, patients who present with advanced disease, includ-
ing large and/or rapidly growing lesions, recurrent lesions,
and regional metastases, have also increased in number.
These patients risk invasion by the tumor into deep struc-
tures including the facial nerve [1]. Tumor involvement or
intraoperative injury to the facial nerve causes cosmetic
and functional morbidity, including brow ptosis, corneal
exposure, sagging of the lower lip, and inability to show the
lower teeth on the affected side.
Fortunately, the incidence of facial nerve dysfunction at
first presentation is rare. A preoperatively intact facial nerve
can often be dissected away from the tumor with exposure
and intra-operative protection of the nerve. However, facial
nerve paresis (weakness) or paralysis is possible after such
Abstract
Background Most patients with head and neck skin tumors
present with normal facial nerve function. A common treat-
ment strategy for these patients is facial nerve preservation
surgery, although the degree to which the nerve is success-
fully preserved is still unclear. Data on the incidence and
recovery of facial nerve dysfunction are woefully lacking
in the field of dermato-oncology.
Methods In 23 patients with normal preoperative facial
nerve function, we retrospectively reviewed twenty-six
head and neck surgical interventions that included facial
nerve exposure and protection, focusing particularly on the
differences in outcome between intraparotid and extrapa-
rotid exposure of the facial nerve branches.
Results Eleven of the 26 cases (42.4%) developed transient
paresis, but only one (3.8%) developed permanent pare-
sis. Of 41 dissected facial nerve branches, 14 developed
transient paresis (34.1%) and one, a marginal mandibular
branch, developed permanent paresis (2.4%). The branches
most susceptible to developing paresis were the temporal
(4/6 branches, 66.7%) and marginal mandibular branches
(8/17 branches, 47.1%). Although the rate of paresis was
higher, and ensuing recovery period slightly longer in the
extraparotid dissection group compared to the intraparotid
dissection group, there were no statistically significant
differences between the two groups. The extraparotid and
* Yasuhiro Nakamura
ynakamur@saitama-med.ac.jp
1
Department of Skin Oncology/Dermatology, Saitama
Medical University International Medical Center, 1397-1
Yamane, Hidaka, Saitama 350-1298, Japan
2
Department of Dermatology, Faculty of Medicine, University
of Tsukuba, Tsukuba, Japan