original article Dental Press Endod. 2015 May-Aug;5(2):56-60 © 2015 Dental Press Endodontics 56 Use of peracetic acid as irrigating agent in Endodontics ABSTRACT The irrigation of the root canal system contributes ef- fectively to appropriate cleanness and antisepsis, thus rendering endodontic treatment more successful. An ideal irrigation protocol was suggested in order to over- come the limitations of commonly used irrigants, in addition to enhancing antisepsis. This protocol recom- mends the use of sodium hypochlorite during biome- chanical preparation, followed by the use of a chelating agent, and again the use of an agent with antimicrobial action. However, it demands considerable clinical time. An alternative to reducing that time would be the use of a final irrigating agent contemplating both chelating and antimicrobial actions. Thus, it has been suggested that peracetic acid (PAA) be used as a substitute for EDTA for final irrigation, since this substance has shown good antimicrobial potential associated with chelating capacity. Some studies have been conducted in order to analyze the effectiveness of its use as an irrigating solution in Endodontics. This literature review aims to present to clinicians and specialists in Endodontics the properties of this irrigating solution by providing rel- evant information on its effectiveness and feasibility in the endodontic practice. Keywords: Peracetic acid. Irrigating solution. Chelating agent. Contact address: Samuel Lucas Fernandes Faculdade de Odontologia de Bauru – USP Al. Octávio Pinheiro Brisolla, 9-75 - CEP: 17.012-901 – Bauru/SP - Brazil E-mail: samuel.lukas.usp@gmail.com Submitted: May 19, 2015. Revised and accepted: June 26, 2015. How to cite this article: Fernandes SL, Tartari T, Bronzato JD, Bramante CM, Vivan RR, Andrade FB, Duarte MAH. Use of peracetic acid as irrigating agent in Endodontics. Dental Press Endod. 2015 May-Aug;5(2):56-60. DOI: http://dx.doi.org/10.14436/2358-2545.5.2.056-060.oar » The authors report no commercial, proprietary or inancial interest in the prod- ucts or companies described in this article. DOI: http://dx.doi.org/10.14436/2358-2545.5.2.056-060.oar Samuel Lucas FERNANDES 1 Talita TARTARI 2 Juliana Delatorre BRONZATO 3 Clóvis Monteiro BRAMANTE 4 Rodrigo Ricci VIVAN 5 Flaviana Bombarda de ANDRADE 5 Marco Antonio Hungaro DUARTE 6 1 Professor of Endodontics, Faculdade Mineirense (FAMA), Mineiros, Goiás, Brazil. 2 PhD resident in Endodontics, Universidade de São Paulo (USP), School of Dentistry, Bauru, São Paulo, Brazil. 3 PhD resident in Microbiology, University of Dundee, Scotland. 4 Full professor, Cosmetic Dentistry, Endodontics and Dental Material, Chairman, Pontifícia Universidad Catolica Madre y Maestra, Graduate Program in Endodontics, Dominican Republic. 5 PhD professor, Universidade de São Paulo (USP), School of Dentistry, Department of Cosmetic Dentistry, Endodontics and Dental Material, Bauru, São Paulo, Brazil. 6 Associate professor, Universidade de São Paulo (USP), School of Dentistry, Department of Cosmetic Dentistry, Endodontics and Dental Material, Bauru, São Paulo, Brazil. Chairman of Endodontics, Universidade de São Paulo (USP), School of Dentistry, Graduate Program in Applied Dental Sciences, Bauru, São Paulo, Brazil.