Journal of Neuroradiology (2014) 41, 87—91 Available online at ScienceDirect www.sciencedirect.com TECHNICAL NOTE The Pressure Cooker Technique for the treatment of brain AVMs René Chapot a,* , Paul Stracke a , Aglaé Velasco a , Hannes Nordmeyer a , Markus Heddier a , Michael Stauder a , Petra Schooss a , Pascal J. Mosimann a,b a Alfried-Krupp Krankenhaus Hospital, Department of Intracranial Endovascular Therapy, Alfried-Krupp Strasse 21, 45131 Essen, Germany b Centre Hospitalier Universitaire Vaudois, University of Lausanne, Department of Radiology and Neuroradiology, CH-1011, rue du Bugnon 46, Lausanne, Switzerland KEYWORDS Brain AVM; Embolization; Onyx; Coils; Glue; Pressure cooker Summary Arteriovenous malformations (AVMs) may be cured by injecting liquid embolic agents such as Onyx. Reflux, however, can sometimes be difficult to control and may jeop- ardize a complete embolization. The pressure cooker technique (PCT) was designed to create an anti-reflux plug by trapping the detachable part of an Onyx-compatible microcatheter with coils and glue in order to obtain wedge-flow conditions, thereby enabling a better understanding of macrofistulous AVMs and a more comprehensive, forceful and controlled Onyx embolization. The PCT might enlarge the range of AVMs amenable to endovascular cure. Three illustrative cases are presented. © 2013 Published by Elsevier Masson SAS. Introduction Brain arteriovenous malformations (AVMs) may be cured with liquid embolic agents such as Onyx [1]. According to the instructions for use, Onyx should be injected slowly over several minutes to create a safe proximal plug and Abbreviations: AVM, Arteriovenous Malformation; PCT, Pressure Cooker Technique; IC, Internal Carotid Artery; DMSO, Dimethyl Sulf- oxide; NBCA, n-butyl cyanoacrylate. Portions of this work were presented as an abstract and oral presentation at the ABCWIN Seminar in Val d’Isère, France, January 17th, 2013. Corresponding author. Tel.: +49 201 434 2556; fax: +49 201 434 2375. E-mail address: rene.chapot@krupp-krankenhaus.de (R. Chapot). minimize backflow. Multiple cycles of short-lived injections interspaced by several waiting periods are often required which may disrupt the progression of Onyx through the nidus, thereby forcing one to prematurely abort the proce- dure. We describe a new method to avoid reflux and enable a more comprehensive, forceful and continuous injection of Onyx that we have called the pressure cooker technique (PCT). Technique The PCT consists of creating a plug of coils and glue between the tip and the detachment zone of a previously placed DMSO-compatible microcatheter (Sonic, Balt Extrusion, Montmorency, France) [4] to enable a continuous injection of Onyx (Ev3-Covidien, Dublin, Ireland) while avoiding reflux at the same time. To create the plug, a second 0150-9861/$ – see front matter © 2013 Published by Elsevier Masson SAS. http://dx.doi.org/10.1016/j.neurad.2013.10.001