1541 Copyright © 2013, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited. Chapter 77 DOI: 10.4018/978-1-4666-2770-3.ch077 Kevin Yi-Lwern Yap Institute of Digital Healthcare, WMG, University of Warwick, UK The Evolving Role of Pharmacoinformatics in Targeting Drug-Related Problems in Clinical Oncology Practice ABSTRACT The rapid growth of the internet and the World Wide Web has led to the development of pharmacoinformat- ics technologies to assist oncology healthcare professionals in delivering optimum pharmaceutical care and health-related outcomes. The proliferation of online health information has also empowered patients with cancer with the knowledge to better participate in the management of their own condition. This chapter introduces the evolving roles of pharmacoinformatics in oncology and discusses some problems that have arisen due to these technologies. Various pharmacoinformatics channels for practitioners and patients are described together with drug interaction parameters that are clinically relevant to oncology clinicians. Additionally, this chapter addresses certain quality issues associated with online anticancer drug interactions and proposes several design principles for developers of pharmacoinformatics tools. Finally, readers will be given an insight as to how pharmacoinformatics can be harnessed for the future improvement of pharmaceutical care in patients with chronic diseases such as cancer.