Pharmacologyonline 3: 581-589 (2009) Kaushik et al 581 IN-VITRO ANTIOXIDANT ACTIVITY OF EXTRACTS OF AVIPATTIKAR CHURNA Ujjwal Kaushik, Prachiti Lachake, C. S. Shreedhara, H. N. Aswatha Ram* *Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal – 576 104, India. Summary Free radicals are highly reactive chemical species indicated in various diseases and ailments. In order to study the antioxidant ability of Avipattikar churna, the aqueous and methanolic extracts of Avipattikar churna was evaluated for in vitro antioxidant potential. The free radical scavenging activity was carried out using the reactivity of extracts towards different radicals such as 2,2 – Azino bis (3-ethyl Benzo Thiazole – 6 – Sulphonic acid (ABTS), 1,1- Diphenyl-2- Picryl Hydrazine (DPPH) and 1:10- Phenanthroline hydrate (O-phenenthroline). The superoxide scavenging activity was measured by spectrophotometric method using (Nitroblue tetrazolium) NBT. The total antioxidant potential of aqueous and methanolic extracts of Avipattikar churna was also evaluated. Keywords: Antioxidant, Avipattikar churna, Free radical scavenging * Corresponding author: Tel: +91 820–2922482 Fax: +91 820–2571998 E-mail address: aswatharam@gmail.com aswatharam.hn@manipal.edu