www.jss-journal.com Page 1 Journal of Separation Science Received: 12 26, 2016; Revised: 05 10, 2017; Accepted: 05 11, 2017 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/jssc.201601454 . This article is protected by copyright. All rights reserved. Simple, rapid, and environmentally friendly method for the separation of isoflavones using ultra-high performance supercritical fluid chromatography Wenjie Wu 1,2 , Yuan Zhang 1,3,a , Hanqiu Wu 1 , Weie Zhou 1 , Yan Cheng 1 , Hongna Li 1 , Chuanbin Zhang 1 , Lulu Li 2 , Ying Huang 2 , Feng Zhang 1, ∗ 1 (Institute of Food Safety, Chinese Academy of Inspection & Quarantine, Beijing 100176, China) 2 (School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) 3 (Department of Pharmacy, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021 China) *Correspondence: Professor Feng Zhang, Institute of Food Safety, Chinese Academy of Inspection & Quarantine, Beijing 100176, China E-mail: fengzhang@126.com Fax:+86-010-53898008