Page 1/17 Randomized clinical trial to assess the protective eｨcacy of a Plasmodium vivax CS synthetic vaccine Socrates Herrera (  sherrera@inmuno.org ) Caucaseco Scientiｦc Research Center https://orcid.org/0000-0001-6354-0184 Myriam Arevalo-Herrera Centro de Investigación Cientíｦca Caucaseco Michelle Larmart-Delgado Malaria Vaccine and Drug Development Center (MVDC) Maria Alejandra Caicedo Malaria Vaccine and Drug Development Center (MVDC) Juliana Henao-Geraldo Malaria Vaccine and Drug Development Center (MVDC) Angelica Castellanos Malaria Vaccine and Drug Development Center (MVDC) Xiomara Gaitan Malaria Vaccine and Drug Development Center (MVDC) Sonia Herrera Caucaseco Scientiｦc Research Center Jean-Christophe Devaud Biochemistry Department, University of Lausanne André Panatier Biochemistry Department, University of Lausanne Jose Oñate Centro Médico Imbanaco Giampietro Corradin University of Lausanne Article Keywords: Plasmodium vivax, circumsporozoite protein, malaria, vaccines, clinical trial, Phase II trial, Colombia DOI: https://doi.org/10.21203/rs.3.rs-374553/v1