Research Article
Characteristics of Acute Appendicitis before and during the
COVID-19 Pandemic: Single Center Experience
A. Bosak Verˇ si´ c ,
1
M.
ˇ
Sestan ,
2
I.
´
Cepi´ c ,
3
H. Nikoli´ c ,
1
N. Bukvi´ c ,
1
S. Srˇ sen Medanˇ ci´ c ,
1
D. Hasandi´ c ,
1
and M. Zeli´ c
3
1
Pediatric Surgery Department, University Hospital Rijeka, Rijeka 51000, Croatia
2
Medical Faculty, University Hospital Rijeka, Rijeka 51000, Croatia
3
Surgery Department, University Hospital Rijeka, Rijeka 5100, Croatia
CorrespondenceshouldbeaddressedtoA.BosakVerˇ si´ c; anabosak@yahoo.com
Received 26 November 2021; Accepted 28 January 2022; Published 24 February 2022
AcademicEditor:RobertoCirocchi
Copyright © 2022 A. Bosak Verˇ si´ c et al. is is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is
properly cited.
e aim of the study was to investigate whether the COVID-19 pandemic caused an increased incidence of complicated ap-
pendicitis due to the late presentation when compared to the pre-COVID-19 period. Summary Background Data. Acute ap-
pendicitisisoneofthemostcommonsurgicalemergencies.Duringthecoronavirus-19(COVID-19)pandemic,therehasbeena
reporteddelayinthepresentationofsomeurgenciestotheemergencyhospitaldepartments. Methods.Atotalof427patientswho
underwent surgical treatment due to suspected acute appendicitis from June 2019 to November 2020 were retrospectively
includedinthisstudy.epatientsweredividedintotwogroups:thefirst(pre-COVID-19)groupconsistedofpatientswhohad
surgery before the onset of COVID-19 pandemic (n � 240), while the second (COVID-19) group consisted of those who were
operated during the COVID-19 pandemic (n � 187). e primary outcome of the study was to compare the incidence of
perforated appendicitis before and during the onset of COVID-19. Results. Overall, 84 patients (19.67%) were diagnosed with
perforatedappendicitis.Wefoundaweaksignificance(p � 0.085)intherateofperforatedappendicitisbetweenthepre-COVID-
19(17.08%)andtheCOVID-19era(22.99%). Conclusions.Wedidnotobserveanysignificantdifferenceinthecomplicationsof
acuteappendicitisbeforeandduringtheCOVID-19pandemicinauniversityhospitalinRijeka.Anemergentmedicalcareshould
always be accessible.
1. Introduction
Attheendof2019,anewcoronaviruswasidentifiedasthe
cause of a cluster of pneumonia cases in Wuhan, China. It
rapidlyspreads,resultinginanepidemicthroughoutChina,
followedbyanincreaseinthenumberofcasesincountries
around the world. In February 2020, the World Health
Organization (WHO) designated the disease COVID-19,
which stands for coronavirus disease 2019 [1, 2]. Many
countriesstruggledtostaveofftherapidspreadofCOVID-
19 by implementing different strategies. In most countries,
including Croatia, authorities have instructed the public to
stay at home and to avoid unnecessary socializing. In our
hospital,asignificantdecreaseinthenumberofemergency
department (ED) examinations has been noted. However,
urgent medical cases have continued to appear along the
current outbreak, and their diagnosis needs to be made
appropriately. Delayed diagnosis and treatment of these
conditions may lead to a significant morbidity that may
outweigh the harm caused by COVID-19 infection [3].
Acute appendicitis is one of the most common abdominal
surgicalemergenciesingeneralwitha7%lifetimerisk[4–7].
Eventhough antibiotics have been described as a type of
therapy for uncomplicated appendicitis, surgery still re-
mainsthepreferabletreatmentmodality[8].Earlydiagnosis
of appendicitis and consequent appropriate surgical treat-
ment is important as it may prevent complications such as
appendix perforation, abscess formation, and other post-
operative complications including death [9]. During the
COVID-19 pandemic, it is expected that more patients will
Hindawi
Emergency Medicine International
Volume 2022, Article ID 4541748, 5 pages
https://doi.org/10.1155/2022/4541748