1 Supporting Information An efficient one-pot approach for the regio and diastereoselective synthesis of trans-dihydrofuran derivatives: Cytotoxicity and DNA-binding studies Yellaiah Tangella, Kesari Lakshmi Manasa, V. LaxmaNayak, Manda Sathish, B. Sridhar, Abdullah Alarifi, Narayana Nagesh* and Ahmed Kamal* List of contents X-ray Crystallographic data of compound 1b…….……………………………………….2-3 Figures 1, 2 and COSY Spectra of compound 1e …………………………………………4-5 1 H and 13 C NMR spectras of compounds 1a-x and 2a-j……………………………………5-39 \ Electronic Supplementary Material (ESI) for Organic & Biomolecular Chemistry. This journal is © The Royal Society of Chemistry 2017