CLINICAL INVESTIGATION
Management of Sleep Disorders in Community-Dwelling Older
Women and Men at the Time of Diagnosis
Paula Pop, MD,* Susan E. Bronskill, PhD,
†‡§
Katrina L. Piggott, MD,
¶
Nathan M. Stall, MD,
†‡¶
Rachel D. Savage, PhD,
†
Jessica D. Visentin, PharmD,
†
Lisa M. McCarthy, Pharm D, MSc,
†∥
**
Vasily Giannakes, MPH,
†§
Wei Wu, MSC,
†
Andrea Gruneir, PhD,
†§††
Jodi M. Gatley, MPH,
§
and
Paula A. Rochon, MD, MPH
†‡§¶
OBJECTIVES: Sedative and hypnotic medications are associ-
ated with harm, and guidelines suggest limiting their use. Only
limited evidence has described how older adults are managed
following an initial sleep disorder diagnosis. We aimed to
describe clinical management patterns of sleep disorders in
older women and men at the time of initial diagnosis.
DESIGN: Population-based retrospective cohort study using
linked administrative databases.
SETTING: Ontario, Canada.
PARTICIPANTS: Community-dwelling adults aged 66 and
older, diagnosed with a new sleep disorder by a primary
care provider (n = 30 729; 56% women and 44% men).
We compared women and men for each outcome.
MEASUREMENTS: The primary outcome was prescription
of a medication used for sleep within 30 days of a new sleep
disorder diagnosis. Additional analysis included medical
investigations such as sleep studies and visits to specialists
who manage obstructive sleep disorders within 90 days of
diagnosis.
RESULTS: Among the 30 729 older adults with a new sleep
disorder diagnosis, 5512 (17.9% total; 18.8% of women and
16.9% of men) were prescribed a medication used for sleep.
Compared with men, women were somewhat more likely to
be prescribed at least one sedative medication (adjusted odds
ratio = 1.09; 95% confidence interval = 1.03-1.16). A total of
2573 (8.4%) older adults underwent a sleep study, and 3743
(12.2%) were evaluated by a specialist; both occurred more
commonly in men.
CONCLUSION: In our cohort, almost 1 in 5 older adults
with a new sleep disorder diagnosis were prescribed a medi-
cation used for sleep; of these, a higher proportion were
women. Comparatively few older adults were further evalu-
ated; of these, a higher proportion were men. Our study high-
lights the high rates at which medications are prescribed to
older adults with a new sleep disorder diagnosis and identifies
potential sex differences in the management of such diagno-
ses. J Am Geriatr Soc 00:1-8, 2019.
Key words: medications used for sleep; sleep disorders;
women and men; older adults
D
ifficulty sleeping is common with advanced age,
1-4
with a self-reported insomnia prevalence of roughly
50% in older adults.
5
Chronic sleep-related issues were
linked with an increase in morbidity and associated with
psychiatric disorders.
6-8
The American College of Physicians’
clinical practice guideline on the management of chronic
insomnia disorder suggests that the initial management of
insomnia in older adults should focus on nonpharmacologic
interventions.
9
Additional guidelines also support focusing
on behavioral modification as the first-line treatment for
From the *Department of Medicine, University of Toronto, Toronto,
Canada;
†
Women’s College Research Institute, Women’s College Hospital,
Toronto, Canada;
‡
Institute of Health Policy, Management and Evaluation,
Dalla Lana School of Public Health, University of Toronto, Toronto,
Canada;
§
ICES, Toronto, Ontario, Canada;
¶
Department of Medicine,
Division of Geriatric Medicine, University of Toronto, Toronto, Canada;
∥
Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada;
**Department of Family and Community Medicine, University of Toronto,
Toronto, Canada; and the
††
Department of Family Medicine, University of
Alberta, Edmonton, Canada.
Address correspondence to Paula A. Rochon, Women’s College Research
Institute, Women’s College Hospital, 76 Grenville Street, Toronto, Ontario,
Canada. E-mail: paula.rochon@wchospital.ca
Funding sources and previous presentations: This work was supported by
ICES, funded by an annual grant from the Ontario Ministry of Health and
Long-Term Care. Paula A. Rochon holds the Retired Teachers of Ontario
(RTO/ERO) Chair in Geriatric Medicine at the University of Toronto. The
preliminary results of this study were presented as a poster presentation at
the Canadian Geriatrics Society 38th Annual Scientific Meeting in
Montreal, QC (April 2018).
DOI: 10.1111/jgs.16038
JAGS 00:1-8, 2019
© 2019 The American Geriatrics Society 0002-8614/19/$15.00