Accepted Article Preview: Published ahead of advance online publication Deletion of the GAA repeats from the human frataxin gene using the CRISPR-Cas9 system in YG8R-derived cells and mouse models of Friedreich Ataxia D L Ouellet, K Cherif, J Rousseau, J-P Tremblay Cite this article as: D L Ouellet, K Cherif, J Rousseau, J-P Tremblay, Deletion of the GAA repeats from the human frataxin gene using the CRISPR-Cas9 system in YG8R-derived cells and mouse models of Friedreich Ataxia, Gene Therapy accepted article preview 26 December 2016; doi: 10.1038/gt.2016.89. This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication. NPG are providing this early version of the manuscript as a service to our customers. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers apply. Received 8 November 2016; accepted 19 December 2016; Accepted article preview online 26 December 2016 © 2016 Macmillan Publishers Limited. All rights reserved.