A367 SLEEP, Volume 42, Abstract Supplement, 2019 B. Clinical Sleep Science and Practice IX. Sleep and Psychiatric Disorders compliance monitoring system. (ResScan by Resmed version 5.7.0) and medication usage data was collected. Results: 11 patients with OSA with AHI <10 and AHI > 40 were excluded to match the OSA severity both group. Mean AHI was 20.6 with CPAP poor-compliant group and 23.0 with CPAP com- pliant group and there were no age difference. All 8 female patients with both OSA and panic disorder failed to adapt to CPAP. Number of medication used for panic disorder before and after CPAP among non compliant group increased from 3.67 to 4.47, however for CPAP compliant group, it dropped signifcantly(from 3.27 to 1.44). HAM-A dropped signifcantly among CPAP compli- ant group(30.4 to 12.5) Conclusion: For comorbid panic disorder and OSA, CPAP com- pliance can be lower, however, managing OSA can be crucial. Support (If Any): 0913 EXPLORING THE RELATIONSHIP BETWEEN SLEEP AND DEPERSONALIZATION Eman Alhelali, Teresa Arora Psychology, Zayed University, Abu Dhabi, United Arab Emirates. Introduction: Depersonalization is characterized by a state in which an individual’s feelings and thoughts seem unreal and not to belong to themselves. Depersonalization disorder (DPD) is a psychological condition whereby an individual feels dissociated/ disconnected from their thoughts, feelings and body. DPD has been previously linked to other psychological conditions including depression and anxiety, both of which have a strong association with sleep. However, there is very little known about the relation- ship between sleep and depersonalization. Methods: A cross-sectional study was conducted to assess the potential relationship between subjective episodes of depersonal- ization and sleep in female university students in the United Arab Emirates. A total of 100 participants were recruited to the study and completed the Pittsburgh Sleep Quality Index (PSQI) as well as the Cambridge Depersonalization Scale (CDS) which deter- mined duration and frequency of depersonalization episodes, as well as a total score. Wrist actigraphy was administered to 37 par- ticipants for two days/nights to objectively estimate sleep duration and sleep effciency (%). Results: The results showed that PSQI global score was positively correlated with both CDS frequency and CDS total score, where r=0.22, p<0.05 and r=0.21, p<0.05, respectively. Subjective sleep duration, obtained from the PSQI, was not signifcantly correlated with any CDS outcome. CDS total score was positively corre- lated with both depression (r=0.35, p<0.001) and anxiety (r=0.36, p<0.001), which is in line with previous fndings. Actigraphy esti- mated average sleep effciency was not, however, signifcantly asso- ciated with DPD, χ 2 =0.56, p>0.05. Conclusion: This is the frst study to primarily focus on the rela- tionship between sleep and depersonalization and provides ini- tial evidence about the role of sleep in this dissociative disorder. Subjective sleep quality but not sleep duration, is signifcantly associated with episodes of depersonalization, but this needs to be confrmed in a larger sample and across different populations. Objective estimate sleep also needs to be incorporated into future studies for at least seven days/nights to ensure comprehensive sleep data is obtained in naturalistic settings. Support (If Any): N/A 0914 THE EXPERIENCE OF CLAUSTROPHOBIA AND CONTINUOUS POSITIVE AIRWAY PRESSURE THERAPY Patricia Dettenmeier, DNP, PHDc St Louis University, St Louis, MO, USA. Introduction: Healthcare is dominated by the biomechanical body disregarding the lived experience. Effective continuous positive airway pressure (CPAP) therapy requires skillful use; claustrophobia may interfere with this. What causes claustropho- bia, fear of enclosed spaces, is different for individuals; ability to use CPAP varies. None have examined the lived experience of claustrophobia and CPAP therapy resulting in a critical gap in knowledge. This interpretive phenomenological study explored the lived experience of claustrophobia in adults with sleep apnea prescribed CPAP. Methods: Participants were recruited from a university-based sleep disorders center in a large Midwest urban area. Four research ques- tions focusing on the meaning of claustrophobia, bodily sensations of claustrophobia, lifetime experiences and coping were addressed in two semi-structured interviews about one month apart. Participants drew a picture of what claustrophobia was like for them. Questionnaires described the sample and triangulated interview data: demographics, Adverse Childhood Experiences (ACES), Epworth Sleepiness Scale, Beck Anxiety Inventory, Claustrophobia Questionnaire, Patient Health Questionnaire-9, and Likert-type scales for anxiety, depression, claustrophobia. Results: To date 12/14 subjects aged 40-68 have completed both interviews. Inter-subject variability exists, but participants gener- ally have multiple ACES, mild to severe sleepiness, anxiety, and depression. Participants identifed signifcant claustrophobia trig- gers beginning in childhood including CPAP mask, crowds, being tied down, MRI, and items around the neck. Participants embody claustrophobia with palpitations, sweating, suffocating/drowning feeling, and lightheartedness. Preliminary themes are emerging: Life altering events (“panic in the MRI” and “babysitter put me in the dark basement for my nap and locked the door.”); Altered bedtime routine (“dread going to bed, put it off as long as possible”; “nothing can touch my neck when I am sleeping”; and, “have to sleep with the TV/light on”); Escape (“need to get away”; “avoid crowds/busy shopping times”; “have to take the mask off for a while”); Coping (“do this for my health”; ‘think about someplace nice”; and, “all about the right mask.”) Conclusion: Claustrophobia, often caused by a life altering event, modifes daytime/bedtime routines and CPAP use. CPAP coping skills vary based on resources. Support (If Any): Potter Scholarship Fund 0915 THE EFFECTS OF ESZOPICLONE ON SPINDLES, SLOW OSCILLATIONS AND THEIR COORDINATION IN HEALTH AND SCHIZOPHRENIA Dimitris Mylonas, PhD 1 , Charmaine Demanuele, PhD 1 , Bengi Baran, PhD 1 , Roy Cox, PhD 2 , Robert Stickgold, PhD 2 , Dara S. Manoach, PhD 1 1 Harvard Medical School, Boston, MA, Department of Psychiatry, Massachusetts General Hospital, Charlestown, MA, USA, 2 Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA. Downloaded from https://academic.oup.com/sleep/article/42/Supplement_1/A367/5451586 by guest on 29 September 2022