Pharmacy Education (2021) 21(2) 93 - 97 https://doi.org/10.46542/pe.2021.212.9397 Pharmacy Education 21(2) 93 - 97 93 ISSN 1477-2701 online © 2021 FIP IAI CONFERENCE RESEARCH ARTICLE The evaluation of compounding prescription and its availability of a licensed product for children at a private hospital in Yogyakarta, Indonesia Dina Christin Ayuning Putri, Maria Dorensia Ku Nanga, Sri Hartati Yuliani Faculty of Pharmacy, Sanata Dharma University, Yogyakarta Special Region, Indonesia, Introduction Providing medicine for paediatric patients is a huge challenge, including the lack of information on drug dosages and the availability of dosage to form the formulas. Medication errors and serious risks are also more common in children than adults (C. Wiedyaningsih et al., 2012). Besides, the need for treatment in paediatric patients is certainly not the same as in adults because the physiology of the paediatric patients’ bodies must be considered different in terms of pharmacokinetics, dosage, route of administration and adherence. That is the reason why a study for paediatric medication is required. An extemporaneous preparation or compounded drug is commonly used as a medication for paediatrics (Widyaswari & Wiedyaningsih, 2012). Compounding is an activity of changing dosage form or mixing drugs into a new dosage form which is needed for the patient (Jackson & Lowey, 2010). It has a high risk and should be of concern because there are many undesirable events such as pharmaceutical problems, drug interactions, medication errors, quality of concoctions, and bacterial contamination problems. However, drug compounding is generally a solution to the limitation of drug formulas for paediatrics (C. Wiedyaningsih et al., 2012). There are some alternatives to drug compounding for paediatric patients. Divided medicinal powder, syrup, dispersible powder/tablet, etc., are some dosage formulations that are commonly used. The study from Virginia (2014) showed that 73% of paediatric patients were more likely to get divided medicinal powder as a medication. Divided medicinal powder, also known as “puyer” in Indonesia, has several advantages, such as flexibility in dose adjusting, easy administration, and Keywords Compounding Extemporaneous preparation Licensed drug formula Prescribing profile Correspondence Dina Christin Ayuning Putri Faculty of Pharmacy Sanata Dharma University Yogyakarta Special Region Indonesia dinachristin@usd.ac.id Abstract Introduction: The availability of licensed drug formulas for paediatric patients is still limited, so compounded drugs still exist, especially in the form of divided medicinal powder. Aim: This study aimed to determine the profile of divided medicinal powder prescription and its availability in licensed drug formula for paediatric patients. Methods: This research was a cross-sectional study. Prescriptions containing order to compound divided medicinal powder at a ublic Hospital in Yogyakarta Special Region from January to March 2019, were collected and analysed descriptively. Results: The total collected prescriptions were 152. The total of active substances given to paediatric patients was 38. The most prescribed drug in the hospital was Triamcinolone. There are 34 active substances already available in licensed drug formulas for paediatric patients, so it is better not to be compounded. However, four active substances are not available as licensed product in the drug information handbook in Indonesia, so, it is reasonable to compound to provide a suitable medication (dose and dosage form) for paediatric patients.