Accepted Manuscript Nanoformulation for potential topical delivery of Vismodegib in skin cancer treatment Maria Natalia Calienni, Camilo Febres-Molina, Ramiro Esteban Llovera, Christian Zevallos-Delgado, María Eugenia Tuttolomondo, Donatella Paolino, Massimo Fresta, Haruna L. Barazorda-Ccahuana, Badhin Gómez, Silvia del Valle Alonso, Jorge Montanari PII: S0378-5173(19)30355-2 DOI: https://doi.org/10.1016/j.ijpharm.2019.05.002 Reference: IJP 18332 To appear in: International Journal of Pharmaceutics Received Date: 31 January 2019 Revised Date: 29 April 2019 Accepted Date: 4 May 2019 Please cite this article as: M.N. Calienni, C. Febres-Molina, R.E. Llovera, C. Zevallos-Delgado, M.E. Tuttolomondo, D. Paolino, M. Fresta, H.L. Barazorda-Ccahuana, B. Gómez, S.d.V. Alonso, J. Montanari, Nanoformulation for potential topical delivery of Vismodegib in skin cancer treatment, International Journal of Pharmaceutics (2019), doi: https://doi.org/10.1016/j.ijpharm.2019.05.002 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.