AGA Abstracts previously received an anti-TNF and 17% were currently receiving anti-TNF therapy. CD patients most frequently reported abdominal pain, diarrhea and increased stool frequency as most important symptoms to control. Patients with UC reported diarrhea, increased stool frequency and blood in stools as most important. Complete control of symptoms was the highest priority outcome, but 20 different outcomes were rated as top 3 priorities for patients. Focus group participants consistently stated that the most important component on communicating these data was a free response question asking their number one concern or goal of therapy at every office visit. Based on responses, a one page patient engagement tool was created and iteratively improved with patient feedback. Discussion: Based on quantitative and qualitative results, we have developed a tool to help patients directly communicate their goals of treatment during an office visit to their providers. This will help focus treatment on personalized needs as opposed to standardized patient report outcomes. Tu1259 Quality of Life and Uncertainty in Crohn's Disease Galia Niv, simona bar-yosef, Irit Avni-Biron, Lev Lichtenstein, Ofer Ben Bassat, Yaron Niv, Sivia Barnoy Introduction: Uncertainty has been proved to be a significant factor affecting quality of life in patient with chronic illness. According to Mishel's "uncertainty in illness theory" (1981), uncertainty is generated when components of the stimuli frame lack a cognitive scheme, thus it is more prevalent when information is lacking and in patients recently diagnosed. Another variable that is external to Mishel's theory and was associated with uncertainty in previous studies is self-epistemic authority that expresses the sense of self-expertise. So far, we could not find any study dealing with the uncertainty phenomenon related quality of life in Crohn's disease patients. Aim: To examine the relationship between uncertainty, and quality of life in Crohn's disease patients. The variables related to uncertainty were; informa- tion regarding illness, self-epistemic authority, and duration of illness. Methods: The study was consisted of 105 patients with Crohn's disease, mean age 34.2 years (range 18-50). The research tool was composed of a 5 part questionnaire. The first part included demographic and clinical information; the other four parts examined the main variables of the study: quality of life (The short Inflammatory Bowel Disease Questionnaire), uncertainty (Mishel Uncertainty in Illness Scale), self-epistemic authority (Bar-Tal & Raviv, self-epistemic author- ity questionnaire), and the use of web information regarding Crohn's disease. Results: A positive correlation was demonstrated between uncertainty to quality of life (P<0.001). In contrast to traditional information including books, education and papers that proved a significant factor to reduced uncertainty, we found significant correlation between web health information and uncertainty. This association was stronger in patients with high self-epistemic authority (r=0.53, P=0.001) than in patient with low self-epistemic authority (r=0.26, P= 0.02). This finding was supported with multiple regression analysis that found the using of web information and self-epistemic authority significant factors for uncertainty (P= 0.05, P= 0.001, respectively). In addition, the health-related quality of life was directly correlated with Crohn's disease activity, extent of the disease, specific diet instructions, and employment (P=0.0006, P=0.04, P=0.04, P=0.001, respectively. Conclusion: This is the first study that examined the relationship between quality of life and uncertainty in patients with Crohn's disease. Understanding factors affecting uncertainty and quality of life can provide tools for the caregivers to better treatment of Crohn's disease patients, focusing on web information that nowadays is the popular modality for patients to access current health information and on patient empowerment to increase self-epistemic authority. Tu1260 Contribution of the ‘Hospital Anxiety and Depression Scale' for the Prediction of Psychiatric Disorder Diagnosis in IBD Outpatient Clinics and the Results of the Treatment Omer Yanartas, Ercan Biçakci, Haluk T. Kani, Munkhtsetseg Banzragch, Zeynep Senkal, Kemal M. Kuscu, Ozlen Atug, Nese Imeryuz, Hakan Akin Background: Depression and anxiety disorders are reported to be quite frequent and decreas- ing the quality of life in Inflammatory Bowel Diseases (IBD) patients. Our aim was to determine the contribution of the ‘Hospital Anxiety and Depression Scale' (HADS) for the prediction of psychiatric disorder diagnosis in IBD outpatient clinics and determine the results of the psychiatric treatment . Method: HADS is a self-report test, which measures both the risk and severity of anxiety - depression in physical diseases. Patients with scores higher than the cut-off sent to a psychiatrist certified for SCID (structured clinical interview for DSM IV) which is a validated interview technique for diagnoses. Then patients completed SF-36 tests for health related quality of life and Arizona Sexual Experience Scale (ASEX) test for sexual dysfunction measurement at the baseline visit and also at 6 months thereafter. Results: We prospectively offered HADS test to a total of 214 consecutive IBD outpatients, 177 accepted and completed the test in a mean time of 7 minutes. Scores of 70 patients (38 Ulcerative Colitis, 32 Crohn's Disease) were higher than cut- offs. After SCID interview, 95.7 % (67 out of 70) had a psychiatric diagnosis with a treatment plan. Major depressive (41.4%) and generalized anxiety disorders (14.3%) were the most common diagnoses. Out of 67 patients, 47 of them completed 6 months of the offered psychiatric drug treatment regimen, whereas 20 of them either not accepted or could not complete the regimen. Baseline demographic properties of these two groups were not comparable. We compared the baseline and 6th month measurements of biologic parameters and also the disease activity scores within same group and these were not statistically different (table). All domains of SF-36, and of ASEX, HAD depression and HAD anxiety scores were all statistically better compared with the baseline at the sixth month results, in the group of patients who had completed the psychiatric treatment. Whereas three domains of SF-36 ( general health, mental health, bodily pain) were worse and all others were statistically not differ at the 6th month results in the patient group who could not complete the psychiatric treatment (table). Conclusion: Depression and anxiety disorders was found to be quite frequent in our IBD outpatients (%39.5). HADS is a cheap, quick, easily applied, self- report, paper tool which revealed a very high consistency (%95.7) with the results of professional SCID interview to predict the need of drug treatment for psychiatry. Positive HADS test may alarm gastroenterologist for psychiatry consultation. In our study although receiving psychiatric treatment did not S-840 AGA Abstracts correct the biologic response parameters, it certainly increased all the quality of life parameters also improved sexual dysfunction. Data of IBD group related to the patients 'completed' and 'could not completed' the offered psychiatric treatment; demographics, biological markers, psychiatric assessment tests results at baseline and at six months Statistical comparision done between data set at the baseline visit and the data set at the six months, separately within each group ( psychiatric treatment completed and could not completed groups), p<0.05 accepted as statistically significant Tu1261 The Majority of Inflammatory Bowel Disease Patients Feel That an Elimination Diet Trial Had Resulted in Disease Symptom Improvement Daniel Stein, Imaan Ansari, Jennifer Cahill, Dilpesh Agrawal, Amar S. Naik, Yelena Zadvornova Background: The etiology of inflammatory bowel disease (IBD) is presumed to be due to an abnormal interaction between the immune system and the luminal contents of the intestine. For this reason diet has been examined both as the cause and as the treatment for IBD. Elimination diets (ED) in particular have gained a great deal of patient interest partially for this reason, but also because they are largely without significant risk. Currently the number of patients on ED and the effect these diets have on their disease and medication compliance is not known. Our aim was to describe predictors of ED trials and its effect on medication compliance and disease perception. Methods: Established and confirmed IBD patients were approached during routine clinic visits at a tertiary IBD center to complete an anonymous survey. In addition to demographic information, patients were asked if they had tried any of 10 ED: low residue diet, lactose-free diet, low-FODMAP diet, specific carbohydrate diet, gluten-free diet, paleolithic diet, vegetarian diet, elemental diet, omega- 3/omega-6 enriched diet, or other. If patients had, they were asked about diet compliance, length of diet, perception of disease severity on diet (1-5 scale), provider awareness of ED, and medication compliance on diet. These were analyzed across demographics, SIBDQ, HBI/