Complications in Donors Using Right Liver Graft: Analysis of 280 Consecutive Cases M. Özbilgin a, *, T. Ünek a , T. Egeli a , C. A galar a , S. Ozkardesler b , E. Karadeniz a , H. Ellidokuz c , F. Obuz d , and _ I. Astarcıo glu a a Department of General Surgery, Dokuz Eylul University School of Medicine, _ Izmir, Turkey; b Department of Anaesthesiology and Intensive Care, Dokuz Eylul University School of Medicine, _ Izmir, Turkey; c Department of Medical Informatics and Biostatistics, Dokuz Eylul University School of Medicine, _ Izmir, Turkey; and d Department of Radiology, Dokuz Eylul University School of Medicine, _ Izmir, Turkey ABSTRACT Introduction. Living donor liver transplantation (LDLT) is performed with increasing frequency worldwide due to the shortage of donated organs. It is a life-saving procedure for the recipient, but, on the other hand, a major surgical procedure for healthy donors and it may cause morbidity and even mortality. Patients and Methods. This research was completed at Dokuz Eylül University Faculty of Medicine Hospital General Surgery Department Liver Transplant Unit and included 280 cases (4 with simultaneous liver and kidney transplants from living donors) who underwent donor right hepatectomy for LDLT from June 2000 to June 2016. We analyzed the data of patients retrospectively. Results. Of 280 donor right hepatectomies for LDLT, 181 were male (M; 64.6%) and 99 were female (F; 35.4%) (M/F: 1.82). Mean donor age was 31.2  0.9 years (range, 18e56). Mean donor monitoring duration was 45  2.4 months (range, 3e192 months). Mean body mass index (BMI) was 24.28  2.96 kg/m 2 (range, 18.1e32.42 kg/m 2 ). In our study 72 cases (25.7%) developed postoperative complications. There were 17 Clavien grade 3A, 1 grade 3B, and 5 grade 4A complications and also 1 death due to pulmonary embolism. Conclusion. Together with the increase in living donor surgery, the morbidity and mortality of these cases are becoming controversial. Full donor safety is only possible with appropriate donor choice requiring very detailed studies, a problem-free hepatectomy process, and close postoperative donor monitoring. I N recent times the gold standard for treatment of liver failure is liver transplantation. However, in countries with limited organ donation, the majority of patients lose their lives while on waiting lists. The first successful living donor liver transplantation (LDLT) in 1989 has become a new source of hope for patients with liver failure in recent times. LDLT has three superior features for recipients compared with cadaver transplantation. First, with LDLT the transplantation can occur within a short time frame, thus the morbidity and mortality that may occur during the waiting period is prevented. Second, living donor livers have better quality than cadaver donor livers because the living donors undergo broader more comprehensive medical investigations. The other advantage is that the cold ischemic duration is significantly shorter in LDLT. In theory this advantage should reduce primary graft dysfunction. Although LDLT is a potentially life-saving operation for the recipient, it is a major surgical procedure applied to healthy donors and does not provide any direct therapeutic advan- tage. Donor operations involve some ethical problems due to the major morbidity and mortality that may occur later [1]. *Address correspondence to Mücahit Özbilgin, MD, Dokuz Eylül University School of Medicine Hospital, Mithatpas ¸ a Cad., No: 1606, 35340 Balçova, _ Izmir, Turkey. E-mail: mucahitozbilgin@ gmail.com 0041-1345/17 http://dx.doi.org/10.1016/j.transproceed.2017.01.043 ª 2017 Elsevier Inc. All rights reserved. 230 Park Avenue, New York, NY 10169 580 Transplantation Proceedings, 49, 580e586 (2017)