International Journal of Innovative Technology and Exploring Engineering (IJITEE) ISSN: 2278-3075, Volume-9 Issue-3, January 2020 2806 Published By: Blue Eyes Intelligence Engineering & Sciences Publication Retrieval Number: C9217019320/2020©BEIESP DOI: 10.35940/ijitee.C9217.019320 Abstract: Bio pad wound dressing is one of the current material in wound healing technology. This aim of this paper is to study the effects of dimethicone cross polymer on the biomaterial and to investigate the mechanical properties of the bio pad by the integration of experimental and numerical approach. In vitro uniaxial tensile test was performed to compute the stress-stretch response of the materials using ASTM D412 standard. The determination of material constants for the materials via numerical approach can be done by comparing with two hyper elastic constitutive models (Ogden and Neo-Hookean). The results show that Ogden’s exponent and coefficient for the subject estimated to be (μ = 0.434 MPa, α = 1.299) for Sample 1, (μ = 0.428 MPa, α = 1.424) for Sample 2, (μ = 0.463 MPa, α = 1.256) for Sample 3 and (μ = 0.633 MPa, α = 1.001) for Sample 4 respectively. Meanwhile, value of material constants for Neo-Hookeen were estimated to be (C 1 = 0.00814 MPa), (C 2 = 0.0121 MPa), (C 3 = 0.00597 MPa) and (C 4 = 0.00739 MPa) for Sample 1, Sample 2, Sample 3 and Sample 4 respectively. Therefore, this study could be useful in future studies in analysis of healing especially in dermatology area. Keywords : Bio pad, Neo-Hookean, Ogden, stress-stretch, wound healing. I. INTRODUCTION Skin is the largest cell of human body with a total area of about 20 square feet or approximately 15% from human body weight. Human skin acts as an external protection from microbes and the harmful elements, help in the regulation of body temperature and permits the sensations of touch, heat and cold. Since the earliest centuries of medical science, skin substitution in a form of wound closure has been found very useful, for example in the management of acute burn injuries and post burn reconstruction[1]. Skin substitutes are heterogeneous group of wound coverage materials that aid in replacement of the function of skin. There are many classifications of skin substitutes that has been proposed based on different composition [2]. Skin can be classified as a hyper elastic and non-linear materials as it exhibits a time dependent viscoelastic relaxation and creep back to its initial position [3]. This is due to the arrangement of fibre and collagen in human skin. To ease the understanding of bio pad material, two types of hyper elastic constitutive model have Revised Manuscript Received on January 05, 2020 * Correspondence Author Nur Nabila Mohd Nazali*, Faculty of Mechanical Engineering, Universiti Teknologi MARA (UiTM), Shah Alam, Selangor, Malaysia. Farah Nur Aisha Mohammad Nasir, Faculty of Mechanical Engineering, Universiti Teknologi MARA (UiTM), Shah Alam, Selangor Malaysia. Nor Fazli Adull Manan*, Faculty of Mechanical Engineering, Universiti Teknologi MARA (UiTM), Shah Alam, Selangor, Malaysia. been proposed which is Ogden and Neo-Hookean are used to obtain the stress and strain values of the material. It is also important to gain the relationship between stress and stretch instead of stress-strain relationship in normal elastic material. rectification is not possible. Currently, a biomaterial that can be defined as a synthetic material that is used to replace or restore function to a body tissue and is continuously in contact with body fluids[4]. Due to an advance technology in medical sector, certain injuries can be countered by using bio pad wound dressing. It is one of the potential materials that can be replaced an artificial skin and have a fast recovery in wound healing stages. Bio pad was classified as biomaterial because it has been engineered to interact with biological systems for medical purpose such as bleeding control, and blood loss minimization. Apart from that, dimethicone cross polymer is one of the types of silicone. Basically, the silicone particles itself are unable to penetrate cell membrane in human body. And in this study, the polymer that need to be used which is the dimethicone cross polymer or its scientific name is polydimethylsiloxane (PDMS) created by using the procedures for rapid prototyping of PDMS micro fluids systems. Therefore, the dimethicone cross polymer is suitable for external uses only such as cosmetics ingredients, and body care purposes. For example, it can be used in the treatment of head lice on the scalp [5] and dimethicone is widely used in skin moisturizer for a skin protection. Some cosmetic formulations use dimethicone cross polymer and related to siloxane polymers in concentration of use up to 15% because they are safe as used in cosmetic formulations [6]. It is believed that this polymer can helps to form a protective barrier on the skin, fill in the lines and wrinkles, help reduce inflammation and irritation and form a sort of plastic-like barrier on the outside of the skin. Therefore, dimethicone cross polymer is applied on the top layer of bio pad to obtain the effects or differences it might have on the mechanical properties of the material. Another material used in this study is aloe vera gel which reveals the presence of diverse biologically active compounds associated with curing different ailments such as wound, inflammations, sunburns and many more [7]. Aloe vera has the large range of medicinal properties [8] which is consists of more than 200 different biological active substances. The combination of aloe vera gel and dimethicone cross polymer can cover the wound on the human skin and boost up the healing process and at the same time to know whether they will influence the mechanical properties of the materials or vice versa. Dimethicone Crosspolymer Effect on Bio Pad Material Nur Nabila Mohd Nazali, Farah Nur Aisha Mohammad Nasir, Nor Fazli Adull Manan