_____________________________________________________________________________________________________ *Corresponding author: Email: nilybayram@hotmail.com; Journal of Cancer and Tumor International 2(3): 110-116, 2015, Article no.JCTI.2015.012 SCIENCEDOMAIN international www.sciencedomain.org A Retrospective Study of 137 Dysplastic Nevi: Are a Personal History of Melanoma and Histopathological Factors Associated with High-grade Cytologic Atypia? Nilay Duman 1* , Gül Erkin 2 , Özay Gököz 3 , Sevilay Karahan 4 , Aycan Uğur Kayıkçıoğlu 5 and Ismail Çelik 6 1 Department of Dermatology, Afyonkarahisar Kocatepe University, School of Medicine, Afyonkarahisar, Turkey. 2 Department of Dermatology, Hacettepe University, School of Medicine, Ankara, Turkey. 3 Department of Pathology, Hacettepe University, School of Medicine, Ankara, Turkey. 4 Department of Biostatistics, Hacettepe University, School of Medicine, Ankara, Turkey. 5 Department of Plastic and Reconstructive Surgery, Hacettepe University, School of Medicine, Ankara, Turkey. 6 Department of Preventive Oncology, Hacettepe University, School of Medicine, Ankara, Turkey. Authors’ contributions This work was carried out in collaboration among all authors. Authors ND and GE designed the study, collected data, did the literature search and also wrote the first draft of the manuscript. Author SK performed statistical analyses. Authors ÖG, AUK and İÇ collected data. All authors read and approved the final manuscript. Article Information DOI:10.9734/JCTI/2015/19696 Editor(s): (1) William CS Cho, Queen Elizabeth Hospital, Hong Kong. Reviewers: (1) Anonymous, Creighton University, USA. (2) Bianca Costa Soares de Sa, Skin Oncology Department, Hospital AC Camargo, São Paulo, Brazil. (3) Sandra Aparecida Marinho, State University of Paraiba (UEPB), Brazil. Complete Peer review History: http://sciencedomain.org/review-history/10572 Received 23 rd June 2015 Accepted 25 th July 2015 Published 14 th August 2015 ABSTRACT Aim: The association between the clinical and histopathological features of dysplastic nevi (DN), and the risk of melanoma is not clearly known. Thus, the aim of the present study is to determine if there is an association between the clinical and histopathological features of DN, and grade of Original Research Article