Volume 1 • Issue 1 • 1000104 Madridge J Case Rep Stud. ISSN: 2639-4553 16 Madridge Journal of Case Reports and Studies Case Report Article Open Access Multiple Ileal Atresia with total Colonic Atresia, A Case Report Sarah Magdy Abdelmohsen 1 * and Osman MA 2 1 Pediatric Surgery, Aswan University Hospital, Egypt 2 Headmaster of Pediatric Surgery, Assiut University Hospital, Egypt Article Info *Corresponding author: Sarah Magdy Abdelmohsen Assistant Lecturer Pediatric Surgery Department Aswan University Hospital Egypt Tel: +201012069422 E-mail: sosoramily@yahoo.com Received: June 20, 2017 Accepted: June 24, 2017 Published: June 30, 2017 Citation: Abdelmohsen SM, Osman MA. Multiple Ileal Atresia with total Colonic Atresia, A Case Report. Madridge J Case Rep Stud. 2017; 1(1): 16-19. doi: 10.18689/mjcrs-1000104 Copyright: © 2017 The Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Published by Madridge Publishers Abstract Introduction Intestinal atresia usually detected in the third trimester of pregnancy with different etiologies report by different authors. Case report We had a unique case of multiple ileal atresia, atresia associated with cardiac anomaly and dysmorphic features. Our case had genetic predispositions as she is the 3rd offspring of a consanguineous parent. The 2nd offspring was also a female and died due to neonatal intestinal obstruction. Histopathological examination of our case showed total colon mucosal atrophy associated with absent ganglion cells and disappearance of myenteric plexus. So, we suggest a presence of association for colonic atresia and absent ganglion cells. Conclusion Is there a need to modify the usual classification of intestinal atresia? We recommend that early diagnosis and treatment is important to improve the prognosis in colonic atresia. Keywords: Multiple ileal atresia; Colonic atresia; Colonic aganglinosis. Introduction Atresia—derived from the Greek components a- (“no” or “without”) and tresis (“hole” or “orifice”)—refers to a congenital obstruction with complete occlusion of the intestinal lumen; it accounts for 95% of obstructions [1-5]. Colonic atresia (CA) is a rare cause of congenital bowel obstruction, on average 1 case per year of colonic atresia is being seen in most of the pediatric surgical centers [6]. An incidence (colonic atresia) of 1 in 20,000 lives births and comprise for 1.8−15% of all cases of bowel atresia in newborns [7] [8] [9]. The coexistence of colonic atresia and absent ganglia at histopathological examination presents an etiological and diagnostic challenge. We report a case of multiple ilealatresia with total colonic obstruction associated multiple congenital anomalies for further study. Case report A 5-day old female infant, born at +_ 36ws gestation due to premature rupture of membrane because of polyhydramnios. She delivered by cesarean section, birth weight 2300 gms, AB +ve blood group. ISSN: 2639-4553