Journal Pre-proof Mushroom polysaccharides and jiaogulan saponins exert cancer preventive effects by shaping the gut microbiota and microenvironment in Apc Min/+ mice Imran Khan, Guoxin Huang, Xiao-ang Li, Weilin Liao, Wai Kit Leong, Wenrui Xia, Xiqing Bian, Jianlin Wu, W.L. Wendy Hsiao PII: S1043-6618(19)31145-4 DOI: https://doi.org/10.1016/j.phrs.2019.104448 Reference: YPHRS 104448 To appear in: Pharmacological Research Received Date: 20 June 2019 Revised Date: 19 August 2019 Accepted Date: 5 September 2019 Please cite this article as: Khan I, Huang G, Li X-ang, Liao W, Leong WK, Xia W, Bian X, Wu J, Hsiao WLW, Mushroom polysaccharides and jiaogulan saponins exert cancer preventive effects by shaping the gut microbiota and microenvironment in Apc Min/+ mice, Pharmacological Research (2019), doi: https://doi.org/10.1016/j.phrs.2019.104448 This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2019 Published by Elsevier.