Pharmacologyonline 3: 24-30 (2010) Newsletter Vijay et al. 24 PHYTOPHARMACOLOGICAL PROPERTIES OF WITHANIA COAGULANS: A REVIEW Lambole Vijay *1, , Krishna Murti 1 , Mayank Panchal 1 , Vipul Gajera 1 , Nikhil Joshi 2 1. Department of Pharmacology, Vidyabharti Trust College of Pharmacy, Umrakh, Bardoli, Dist. Surat. Gujarat, India. 2. Maitree Clinic, Bardoli, Dist. Surat. Gujarat, India. Summary In the natural system of medicine many plants have possess a variety of biological activities. There are two species of Withania, small genuses of shrubs distributed in east of the Mediterranean region extending to South Asia are found in India. Withania coagulans Dunal (family: Solanaceae) commonly known as Indian cheese maker, reported to have different phytochemicals like withanolides, withacoagin, coagulan, withaferin and withasomidienone. The different pharmacological activities reported with this shrub are sedative, CNS depressant, antibilious, emetic, antiasthmatic, diuretic, anti-inflammatory; carminative, depurative, used for dyspepsia, flatulence, hepatoprotective activity, antifungal antibacterial activity, hypolipidemic activity and calcium channel blocking activity. So the present paper enumerates an overview of phytochemical and pharmacological properties of withania coagulans. Keywords: withania coagulans, Phytochemicals, pharmacological profile *Curresponding Author Lambole Vijay B. E-mail: vijaylambole@rediffmail.com Contact no. +919725975989 Introduction In the natural system of medicine many plants have possess a variety of biological activities. Withania Coagulans belongs to the genus Withania and family Solanaceae. Withania coagulans Dunal commonly known as Indian cheese maker, reported to have different phytochemicals and pharmacological properties. The actions reported in literature are Ripe fruits-sedative, CNS depressant, antibilious, emetic, antiasthmatic, diuretic, anti-inflammatory; used in chronic liver troubles and strangury. Dried fruits - carminative, depurative; used for dyspepsia, flatulence and strangury. Leaf-alterative, febrifuge. Seeds- anti-inflammatory, emetic, diuretic activity.