1 Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA. Courtney Barker a , Sarah Allison a , Soumaya Zlitni a , Nick Duc Nguyen b , Rahul Das b , Giuseppe Melacini b , Alfredo A Capretta b and Eric D Brown a a Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON L8S 2K1 b Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4M1 Corresponding author. Tel +1 905 525-9140 x22454; fax: +1 905 522 9033. Email address: ebrown@mcmaster.ca (E. Brown)