Revista de Gastroenterología de México. 2018;83(1):3---8
www.elsevier.es/rgmx
REVISTA DE
DE MEXICO
GASTROENTEROLOGIA
´
´
ORIGINAL ARTICLE
Difference of achalasia subtypes based on clinical
symptoms, radiographic findings, and stasis scores
A. Meillier
a
, D. Midani
b
, D. Caroline
c
, M. Saadi
b
, H. Parkman
b
, R. Schey
b,*
a
Departamento de Medicina, Temple University Health System, Philadelphia, Pennsylvania, U.S
b
Departamento de Gastroenterología, Temple University Health System, Philadelphia, Pennsylvania, U.S
c
Departamento de Radiología, Temple University Health System, Philadelphia, Pennsylvania, U.S
Received 16 November 2016; accepted 14 March 2017
Available online 26 August 2017
KEYWORDS
Achalasia;
Barium esophagram;
Esophageal
manometry
Abstract
Introduction: Three subtypes of achalasia have been defined through high-resolution
esophageal manometry: subtype i shows no pressurization with swallows, subtype ii has
increased isobaric panesophageal pressure, and subtype iii has distal esophageal spastic non-
isobaric contractions. Studies describing the subtypes based on radiographic findings, clinical
symptoms, and stasis scores are limited.
Aim: To determine the differences in clinical symptoms, radiographic findings, and stasis scores
for the 3 achalasia subtypes.
Methods: Patients undergoing high-resolution esophageal manometry received a questionnaire
about current symptoms and previous treatments. The questions included the presence of
symptoms and their severity. Barium swallow tests were performed before the high-resolution
esophageal manometry study to evaluate the maximum esophageal diameter. Stasis scores were
calculated using the transit patterns on high-resolution esophageal manometry.
Results: One hundred and eight patients with high-resolution esophageal manometry diagno-
sis of achalasia (n = 8, subtype i; n = 84, subtype ii; n = 16, subtype iii) within the time frame
of 1/2012-6/2015 were included in the study. Sex distribution was similar between the sub-
types. Patient age was younger for subtype i (38 ± 16 years), compared with subtypes ii (55 ± 17
years) and iii (63 ± 17 years) (P=.03). Esophageal symptoms did not differ between subtypes
Please cite this article as: Meillier A, Midani D, Caroline D, Saadi M, Parkman H, Schey R. Diferencia de subtipos de acalasia basados en
síntomas clínicos, hallazgos radiográficos y puntajes de estasis. Revista de Gastroenterología de México. 2018;83:3---8.
*
Corresponding author. Departamento de Gastroenterología, Escuela de Medicina Lewis Katz en Temple University y en Temple University
Health System, Philadelphia, PA, U.S. Tel.: +215-707-9900.
E-mail address: Ron.schey@tuhs.temple.edu (R. Schey).
2255-534X/© 2017 Asociaci´ on Mexicana de Gastroenterolog´ ıa. Published by Masson Doyma M´ exico S.A. This is an open access article under
the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).