Revista de Gastroenterología de México. 2018;83(1):3---8 www.elsevier.es/rgmx REVISTA DE DE MEXICO GASTROENTEROLOGIA ´ ´ ORIGINAL ARTICLE Difference of achalasia subtypes based on clinical symptoms, radiographic findings, and stasis scores A. Meillier a , D. Midani b , D. Caroline c , M. Saadi b , H. Parkman b , R. Schey b,* a Departamento de Medicina, Temple University Health System, Philadelphia, Pennsylvania, U.S b Departamento de Gastroenterología, Temple University Health System, Philadelphia, Pennsylvania, U.S c Departamento de Radiología, Temple University Health System, Philadelphia, Pennsylvania, U.S Received 16 November 2016; accepted 14 March 2017 Available online 26 August 2017 KEYWORDS Achalasia; Barium esophagram; Esophageal manometry Abstract Introduction: Three subtypes of achalasia have been defined through high-resolution esophageal manometry: subtype i shows no pressurization with swallows, subtype ii has increased isobaric panesophageal pressure, and subtype iii has distal esophageal spastic non- isobaric contractions. Studies describing the subtypes based on radiographic findings, clinical symptoms, and stasis scores are limited. Aim: To determine the differences in clinical symptoms, radiographic findings, and stasis scores for the 3 achalasia subtypes. Methods: Patients undergoing high-resolution esophageal manometry received a questionnaire about current symptoms and previous treatments. The questions included the presence of symptoms and their severity. Barium swallow tests were performed before the high-resolution esophageal manometry study to evaluate the maximum esophageal diameter. Stasis scores were calculated using the transit patterns on high-resolution esophageal manometry. Results: One hundred and eight patients with high-resolution esophageal manometry diagno- sis of achalasia (n = 8, subtype i; n = 84, subtype ii; n = 16, subtype iii) within the time frame of 1/2012-6/2015 were included in the study. Sex distribution was similar between the sub- types. Patient age was younger for subtype i (38 ± 16 years), compared with subtypes ii (55 ± 17 years) and iii (63 ± 17 years) (P=.03). Esophageal symptoms did not differ between subtypes Please cite this article as: Meillier A, Midani D, Caroline D, Saadi M, Parkman H, Schey R. Diferencia de subtipos de acalasia basados en síntomas clínicos, hallazgos radiográficos y puntajes de estasis. Revista de Gastroenterología de México. 2018;83:3---8. * Corresponding author. Departamento de Gastroenterología, Escuela de Medicina Lewis Katz en Temple University y en Temple University Health System, Philadelphia, PA, U.S. Tel.: +215-707-9900. E-mail address: Ron.schey@tuhs.temple.edu (R. Schey). 2255-534X/© 2017 Asociaci´ on Mexicana de Gastroenterolog´ ıa. Published by Masson Doyma exico S.A. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).