Open Journal of Applied Sciences, 2014, 4, 103-129
Published Online March 2014 in SciRes. http://www.scirp.org/journal/ojapps
http://dx.doi.org/10.4236/ojapps.2014.43012
How to cite this paper: Kumar, S., et al. (2014) Vibrational Studies of Different Human Body Disorders Using FTIR Spectros-
copy. Open Journal of Applied Sciences, 4, 103-129. http://dx.doi.org/10.4236/ojapps.2014.43012
Vibrational Studies of Different Human Body
Disorders Using FTIR Spectroscopy
S. Kumar
1*
, Reena
2
, S. Chaudhary
1
, Sweety
1
, Deep Chand Jain
3
1
Department of Physics, Medical Physics Research Laboratory, D.A.V. (P.G.) College, Muzaffar Nagar, India
2
Department of Mathematics, Shri K. K. Jain College, Khatauli, India
3
Department of Neurology, Safdarjang Hospital, New Delhi, India
Email:
*
sanjeev1962@yahoo.co.in ,
*
sanjeev1962kumar@rediffmail.com ,
reena_math@rediffmail.com , drdcjain@gmail.com
Received 8 January 2014; revised 15 February 2014; accepted 22 February 2014
Copyright © 2014 by authors and Scientific Research Publishing Inc.
This work is licensed under the Creative Commons Attribution International License (CC BY).
http://creativecommons.org/licenses/by/4.0/
Abstract
Some of the important features of the bands occur in the present study. The band called amide A is
available in all the diseased and healthy controls and the frequency of the band ranges from 3380
cm
−1
to 3480.74 cm
−1
. The band due to C-H band and called hydrocarbon band was found only in
paralytic and Alzheimer diseased along with normal healthy controls. Carbide band (C=C) is found
only in Duchenne muscular dystrophy, paralytic and Alzheimer’s disease patients. Amide I was in-
tact in all disorders with normal persons. Peroxide band (O-O) was found in all the cases of study.
Amide IV band was found in paralytic, muscular dystrophy, Alzheimer’s diseases and normal con-
trols. The amide V band was found in Alzheimer’s diseases only. The appearance or disappearance
of the bands is a good sign to understand the mechanisms at the molecular level. FTIR spectrosco-
py may help in the diagnosis of the disease at the early stage of the onset. This spectroscopy can be
used nicely for the study of hair, vaginal fluid, nails, urine, mucus, semen, synovial fluid, blood,
hemoproteins, skin, and tears for human beings. We can also use it to understand the effect of
adulteration on food and paint technology. FTIR is an indicator to explore the changes occurring at
molecular level.
Keywords
Fourier Transform Infrared (FTIR); ImmunoglobuinG (IgG); Epilepsy (E); Migraine (M); Paralysis
(P); Alzheimer’s Diseases (AD); Duchenne Muscular Dystrophy (DMD)
1. Introduction
Our main attention is concentrated on Fourier Transform Infrared (FTIR) Spectroscopy. This spectroscopy is a
*
Corresponding author.