International Journal of Advances in Medicine | October 2020 | Vol 7 | Issue 10 Page 1492 International Journal of Advances in Medicine Ravi G et al. Int J Adv Med. 2020 Oct;7(10):1492-1497 http://www.ijmedicine.com pISSN 2349-3925 | eISSN 2349-3933 Original Research Article Compliance of surgical antimicrobial prophylaxis practices in the departments of general surgery and orthopaedics at a tertiary care centre in India Gandham Ravi*, Gaurav Chikara, Arkapal Bandyopadhyay, Shailendra Handu INTRODUCTION Antimicrobial (AM) Stewardship Programme practices are at primitive state in Indian healthcare settings despite the existence of standard guidelines, and according to the evidence shown by the national level survey carried out by the Indian Council of Medical Research (ICMR) in the year 2013, only up to 30% of the healthcare institutions have been found out to be practicing the AM stewardship guidelines and recommendations. 1 Analysis of the data regarding the AM consumption between the years 2000 and 2010 shown that there is an increase in the consumption of AM agents with increased usage of the last resort AMs to treat the infections. All these findings have shown the need for the rationale prescription of these agents and the compliance with the guidelines and recommendations. 2 Most of the data at the global level also shows inappropriateness in the surgical AM prophylaxis. 3 Prophylactic AM administration in order to prevent the infection and there by promoting the wound healing without any complications at the surgical site is the core aspect of undertaking any surgical procedure. ABSTRACT Background: Antimicrobial (AM) prophylaxis is one of the major interventions to prevent surgical site infections. The guideline recommendations are meant for helping the surgeons to select the rationale and effective approach while. This study aimed to assess the compliance of surgical AM prophylaxis in terms of choice of antibiotic, duration and timing of administration using standard international and national guidelines. Methods: A prospective observational study was done in General Surgery and Orthopaedics over a period of one year. All the relevant data was collected and analysed. Results were then compared with standard Clinical Practice Guidelines (CPGAS-2013 and ICMR-2017). Results: In terms of choice of AM, 31.32% of the cases from general surgery and 97.59% of the cases from orthopaedics according to ICMR 2017 guidelines; 28.91% of the cases from general surgery and none of the cases from orthopaedics according to CPGAS 2013 guidelines were found to be compliant. In terms of duration of prophylaxis, 28.91% and 22.89% of the cases from general surgery were found to be compliant to ICMR 2017 and CPGAS 2013 guidelines respectively; but none of the cases from orthopaedics were compliant to either of the guidelines. Timing of administration was found to be compliant with the guidelines in both the departments. Conclusions: Surgical prophylaxis practices were found to be partially compliant with the guidelines in the selected departments. Keywords: AM, Antibiotic, Antimicrobial prophylaxis, Antimicrobial stewardship practices, Compliance Department of Pharmacology, All India Institute of Medical Sciences, Rishikesh, India Received: 23 August 2020 Accepted: 08 September 2020 *Correspondence: Dr. Gandham Ravi, E-mail: gandhamravi89@gmail.com Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. DOI: http://dx.doi.org/10.18203/2349-3933.ijam20203996