Our Dermatology Online © Our Dermatol Online 1.2020 50 How to cite this article: Shah FY, Bhat YJ, Zeerak S, Wani R, Hassan Shah I. Cutaneous mastocytosis mimicking hypertrophic scars: A case report. Our Dermatol Online. 2020;11(1):50-52. Submission: 23.02.2019; Acceptance: 04.05.2019 DOI: 10.7241/ourd.20201.12 Cutaneous mastocytosis mimicking hypertrophic Cutaneous mastocytosis mimicking hypertrophic scars: A case report scars: A case report Faizan Younus Shah 1 , Yasmeen Jabeen Bhat 1 , Sumaya Zeerak 1 , Roohi Wani 2 , Iffat Hassan Shah 1 1 Department of Dermatology, Government Medical College, Srinagar, Kashmir University, J&K, India, 2 Department of Pathology, Government Medical College, Srinagar, Kashmir University, J&K, India Corresponding author: Dr. Yasmeen Jabeen Bhat, E-mail: yasmeenasif76@gmail.com INTRODUCTION Mast cell is a type of granulocyte derived from myeloid stem cells. Once thought to be tissue resident basophils, mast cells have been shown to have a unique lineage. The mast cells have a diverse distribution inhabiting the skin, respiratory, gastrointestinal and genitourinary system [1]. Although best known for their role in allergy and anaphylaxis, mast cells are now known to have critical proinflammatory as well as immunoregulatory roles and are intimately linked with wound healing, angiogenesis and blood-brain barrier function [2]. Mast cells exert their functions by means of various medaitors like histamine, leukotrienes, chemokines, cytokines, chymase and tryptase among others. Mastocytosis is a disorder characterized by abnormal mast cell proliferation and accumulation within various organs, most commonly the skin when it is called cutaneous mastocytosis. There are three main types of cutaneous mastocytosis: maculopapular cutaneous mastocytosis, solitary cutaneous mastocytosis and diffuse cutaneous mastocytosis [3]. Telengiectasia macularis eruptive perstans is regarded as a rare variant of cutaneous mastocytosis. The clinical presentation of cutaneous mastocytosis is diverse with lesion morphology varying from macules, papules, plaques and nodules, size ranging from few millimeters to several centimeters, and colour differing from yellow-tan to red-brown. We report a case of cutaneous mastocytosis masquerading as hypertrophic scars. CASE REPORT A 21 year old female patient presented to the out- patient department (OPD) of the department of dermatology of our hospital with the chief complaints of few raised reddish brown to black lesions on the right thigh from 3 months. The lesions were associated with moderate to severe pruritus which would disturb the routine activities of the patient and mandate the use of over the counter antihistaminics for relief. The patient also gave history of non-specific diffuse pruritus which would occur occasionally and had a ABSTRACT Cutaneous mastocytosis are a group of disorders which are characterized by abnormal proliferation and accumulation of mast cells in the skin. We report a case of a 21 year old female who presented with few isolated lesions on the thigh which were initially misdiagnosed as hypertrophic scars by a general practitioner. However, following examination of the case by a dermatologist, a diagnosis of cutaneous mastocytoma was suspected and confirmed with histopathological examination. Key words: Mastocytosis; Hypertrophic scar Case Report