Jebmh.com Original Article J. Evid. Based Med. Healthc., pISSN- 2349-2562, eISSN- 2349-2570/ Vol. 3/Issue 22/Mar. 17, 2016 Page 972 COMPARISON OF OUTCOMES WITH OR WITHOUT OXYGEN SUPPLEMENTATION IN REGIONAL ANESTHESIA Megha Pandurang Tajne 1 , Shweta Shashikant Aswale 2 , Anjali Rakesh Bhure 3 , Manish Ram Vinod Singh Kumar 4 , Heena Dinesh Pahuja 5 , Gopalji Ramesh Gupta 6 , Ajay Vasant Watve 7 , Apoorva Mahendra Garhwal 8 1 Associate Professor, Department of Anaesthesia, NKPSIMS & RC & Lata Mangeshkar Hospital, Digdoh Hills, Hingna Road, Nagpur. 2 Senior Resident/Tutor, Department of Anaesthesia, NKPSIMS & RC & Lata Mangeshkar Hospital, Digdoh Hills, Hingna Road, Nagpur. 3 Professor & HOD, Department of Anaesthesia, NKPSIMS & RC & Lata Mangeshkar Hospital, Digdoh Hills, Hingna Road, Nagpur. 4 Resident, Department of Anaesthesia, NKPSIMS & RC & Lata Mangeshkar Hospital, Digdoh Hills, Hingna Road, Nagpur. 5 Assistant lecturer, Department of Anaesthesia, NKPSIMS & RC & Lata Mangeshkar Hospital, Digdoh Hills, Hingna Road, Nagpur. 6 Resident, Department of Anaesthesia, NKPSIMS & RC & Lata Mangeshkar Hospital, Digdoh Hills, Hingna Road, Nagpur. 7 Senior Resident, Department of Anaesthesia, NKPSIMS & RC & Lata Mangeshkar Hospital, Digdoh Hills, Hingna Road, Nagpur. 8 Resident, Department of Anaesthesia, NKPSIMS & RC & Lata Mangeshkar Hospital, Digdoh Hills, Hingna Road, Nagpur. ABSTRACT BACKGROUND AND OBJECTIVES Oxygen is routinely supplemented in patients of regional anaesthesia. There are many pros and cons in the use of oxygen supplementation and its real benefit. In our study we tried to find out the effect of oxygen supplementation on the haemodynamic parameters, oxygen saturation, post-operative nausea vomiting and wound healing. MATERIAL AND METHODS The study was a prospective randomized controlled trial. Two hundred and forty patients belonging to ASA 1 physical status of either gender, aged 30-65 years were randomly allocated into two equal groups; group O and group N. Group O: Control group in which oxygen was supplemented through Ventimask Group N: Study group in which oxygen was not supplemented. They underwent elective lower abdominal surgery including general surgery, orthopaedics and gynaecological surgeries. Both the groups were compared for haemodynamic parameters, oxygen saturation (SpO2), post-operative nausea vomiting and surgical site infection. RESULTS The mean pulse rate (intra operative) in group O was 83.45±11.82/min. In group N it was 84.01±11.88. The mean systolic blood pressure (intraoperative) in group O was 107.83±13.37/mmHg. In group N it was 106.62±11.03 mmHg. The mean diastolic blood pressure in group O was 72.56±0.51 mmHg and in group N it was 70.75±7.53 mmHg. The mean oxygen saturation in group N was 97.4%±1.09 while in group O it was 99.3%±1.15. There was no statistical significant difference in both the groups for haemodynamic parameters and oxygen saturation (P >0.05). 16 patient had post-operative nausea vomiting in group N while 15 patients in group O. There was no statistical significant difference between the two groups for post-operative nausea vomiting (P>0.05). 12 patients had surgical site infection in group N while the number was 10 in group O. There was on statistical significant difference between the two groups for surgical site infection. (P value was >0.05) CONCLUSION There was no statistically significant difference for pulse rate, blood pressure, post-operative nausea vomiting and surgical site infection in between the two groups i.e. with and without oxygen supplementation groups. KEYWORDS Oxygen supplementation, Haemodynamic parameters, Oxygen saturation, Postoperative nausea vomiting, Surgical site infection. HOW TO CITE THIS ARTICLE: Tajne MP, Aswale SS, Bhure AR, et al. Comparison of outcomes with or without oxygen supplementation in regional anesthesia. J. Evid. Based Med. Healthc. 2016; 3(22), 972-975. DOI: 10.18410/jebmh/2016/222 INTRODUCTION: Ever since the discovery of oxygen, its value is recognized worldwide. Today not a single anaesthetic procedure is done without the consideration of oxygen supplementation. The usefulness and benefits of oxygen administration remained unchallenged until a few decades ago when our understanding of oxidative stress and oxygen toxicity became more comprehensive and a more balanced application of oxygen therapy was proposed. 1 Submission 17-02-2016, Peer Review 02-03-2016, Acceptance 09-03-2016, Published 16-03-2016. Corresponding Author: Dr. Megha Tajne, #10-R, Pioneer Residency Park, Somalwada Square, Wardha Road, Nagpur-440025. E-mail: uikeymegha@rediffmail.com, drshwetaaswale@yahoo.com DOI: 10.18410/jebmh/2016/222