Accepted Manuscript Alanine substitution mutations in the DNA binding region of a global staphylococcal virulence regulator affect its structure, function, and stability Sukhendu Mandal, Semanti Ghosh, Debabrata Sinha, Soham Seal, Avisek Mahapa, Soumitra Polley, Deeya Saha, Keya Sau, Angshuman Bagchi, Subrata Sau PII: S0141-8130(17)32660-0 DOI: doi:10.1016/j.ijbiomac.2018.03.045 Reference: BIOMAC 9267 To appear in: Received date: 21 July 2017 Revised date: 2 March 2018 Accepted date: 11 March 2018 Please cite this article as: Sukhendu Mandal, Semanti Ghosh, Debabrata Sinha, Soham Seal, Avisek Mahapa, Soumitra Polley, Deeya Saha, Keya Sau, Angshuman Bagchi, Subrata Sau , Alanine substitution mutations in the DNA binding region of a global staphylococcal virulence regulator affect its structure, function, and stability. The address for the corresponding author was captured as affiliation for all authors. Please check if appropriate. Biomac(2017), doi:10.1016/j.ijbiomac.2018.03.045 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.