Journal Pre-proof Efﬁcient optimization of a multifunctional catalytic ﬁxed-bed reactor via reduced-order modeling approach Katarzyna Bizon, Gaetano Continillo PII: S0263-8762(20)30556-6 DOI: https://doi.org/10.1016/j.cherd.2020.11.007 Reference: CHERD 4297 To appear in: Chemical Engineering Research and Design Received Date: 5 June 2020 Revised Date: 16 October 2020 Accepted Date: 7 November 2020 Please cite this article as: Bizon K, Continillo G, Efﬁcient optimization of a multifunctional catalytic ﬁxed-bed reactor via reduced-order modeling approach, Chemical Engineering Research and Design (2020), doi: https://doi.org/10.1016/j.cherd.2020.11.007 This is a PDF ﬁle of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the deﬁnitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its ﬁnal form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2020 Published by Elsevier.