This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/bmc.4579 This article is protected by copyright. All rights reserved. Elagawany Mohamed (Orcid ID: 0000-0002-1597-5324) Baclofen Impurities: Facile Synthesis and Novel Environmentally Benign Chromatographic Method for their Simultaneous Determination in Baclofen Mohamed Elagawany a,b , Nehal F. Farid c , Bahaa Elgendy b,d , Esraa H. Abdelmomen e and Nada S. Abdelwahab c,e a Pharmaceutical Chemistry, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt. b Center for Clinical Pharmacology, Washington University School of Medicine and St. Louis College of Pharmacy, St. Louis, MO 63110, USA. C Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. d Chemistry Department, Faculty of Science, Benha University, Benha 13518, Egypt. e Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Nahda University (NUB), Beni- Suef, Egypt Corresponding author Dr. Mohamed Elagawany Faculty of pharmacy, Elgomhoria St., Damanhour, Egypt E-mail address: alfath_tours@yahoo.com.