Clinical Paper Oral Surgery Torus mandibularis bone chips combined with platelet rich plasma gel for treatment of intrabony osseous defects: clinical and radiographic evaluation K. S. Hassan, A. S. Alagl, A. Abdel-Hady: Torus mandibularis bone chips combined with platelet rich plasma gel for treatment of intrabony osseous defects: clinical and radiographic evaluation. Int. J. Oral Maxillofac. Surg. 2012; 41: 1519–1526. Published by Elsevier Ltd on behalf of International Association of Oral and Maxillofacial Surgeons. K. S. Hassan 1,2 , A. S. Alagl 3 , A. Abdel-Hady 4,5 1 Department of Preventive Dental Sciences, Division of Periodontics, College of Dentistry, University of Dammam, Saudi Arabia; 2 Oral Medicine and Periodontology, Faculty of Dental Medicine, Al-Azhar University, Assiut Branch, Egypt; 3 Department of Preventive Dental Sciences, College of Dentistry, University of Dammam, Saudi Arabia; 4 Oral & Maxillofacial Surgery, College of Dentistry, University of Dammam, Saudi Arabia; 5 Oral & Maxillofacial Surgery, Tanta University, Egypt Abstract. The use of platelet rich plasma (PRP) gel in combination with torus mandibularis offers a potentially useful treatment for periodontal osseous defects. Whether this combination enhances the outcome of periodontal regenerative therapy is not known. This study compared the effectiveness of torus mandibularis bone chips alone and when combined with autogenous PRP gel in treating periodontal osseous defects. 24 sites from 12 patients were selected using a split mouth design and determined by a double-blind, randomized, controlled clinical trial. Both sites received a full-thickness mucoperiosteal flap; one intrabony defect was filled with torus mandibularis bone chips alone and the other with torus mandibularis bone chips mixed with PRP gel. There was a 57% gain in the clinical attachment level and 60% reduction in the probing depth for torus mandibularis alone compared to 72% and 68% for sites treated with torus mandibularis and PRP gel (p  0.01). There was a statistically significant difference in the bone dentistry and the marginal bone loss at sites with PRP gel compared to those without gel (p  0.01). The use of mandibular tori as autogenous bone graft combined with PRP gel showed a significant improvement in the clinical outcome of periodontal therapy than mandibular tori alone. Keywords: torus mandibularis; platelet rich plasma; intrabony osseous defects. Accepted for publication 15 February 2012 Available online 6 April 2012 Periodontal therapy is directed towards controlling the infection and regenerating the lost supporting structures. Periodontal regeneration refers to the restoration of supporting tissues of the teeth such as bone, cementum, and periodontal ligament to their original healthy levels before periodontal tissue distraction has occurred. Over the last decades different Int. J. Oral Maxillofac. Surg. 2012; 41: 1519–1526 doi:10.1016/j.ijom.2012.02.009, available online at http://www.sciencedirect.com 0901-5027/01201519 + 08 $36.00/0 Published by Elsevier Ltd on behalf of International Association of Oral and Maxillofacial Surgeons.