Please cite this article in press as: Hsu J-S, et al. Altered brain correlates of response inhibition and error processing in females with obesity and sweet food addiction: A functional magnetic imaging study. Obes Res Clin Pract (2017), http://dx.doi.org/10.1016/j.orcp.2017.04.011 ARTICLE IN PRESS ORCP-665; No. of Pages 10 Obesity Research & Clinical Practice (2017) xxx, xxx—xxx ORIGINAL ARTICLE Altered brain correlates of response inhibition and error processing in females with obesity and sweet food addiction: A functional magnetic imaging study Jui-Sheng Hsu a,b , Peng-Wei Wang c , Chih-Hung Ko d,e , Tsyh-Jyi Hsieh f , Chiao-Yun Chen a,b , Ju-Yu Yen d,g,* a Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan b Department of Radiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan c Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan d Department of Psychiatry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan e Department of Psychiatry, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan f Department of Radiology, Chi-Mei Medical Center, Tainan, Taiwan g Department of Psychiatry, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan Received 25 February 2017; accepted 21 April 2017 KEYWORDS Obesity; Sweet food addiction; Response inhibition; Impulsivity; Error processing; Insula Summary Background: The aim of the present study was to evaluate the impulsivity and brain correlates of response inhibition and error processing among females with obesity and sweet food addiction (O & SFA). Methods: We evaluated the response inhibition and error processing by functional magnetic resonance imaging (fMRI) in subjects with O & SFA and controls. Twenty females with O & SFA and 20 controls were recruited. All subjects performed the event-related designed Go/No-go task under fMRI and completed questionnaires related to food craving and impulsivity. Results: The O & SFA group exhibited a higher score for impulsivity than did the control group. The O & SFA also exhibited lower brain activation when processing response inhibition over the right rolandic operculum and thalamus than controls. * Corresponding author at: Department of Psychiatry, Kaohsiung Medical University Hospital, 100 Tzyou 1st Rd. Kaohsiung City 807, Taiwan. E-mail address: yenjuyu@cc.kmu.edu.tw (J.-Y. Yen). http://dx.doi.org/10.1016/j.orcp.2017.04.011 1871-403X/© 2017 Asia Oceania Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.