BP I BulletinofIntegrative Psychiatry Buletin dePsihiatrieIntegrativa Mini-review on the Basic Genetic Aspects for the Attention Deficit Hyperactivity Disorder (ADHD) Fabian Lungu Fabian Lungu - Department of Biology, Faculty of Biology, Alexandru Ioan Cuza University, B dul Carol I, no 11, 700506 Iasi, Romania ABSTRACT Attention deficit hyperactivity disorder (ADHD) is a common and generally inherited neuropsychiatric disorder that is present in children and adults, and it is considered a multifactorial disorder. Due to the limited effects of genes on the manifestation of the disorder, we wanted to analyze the impact of the genes SNAP25, BAIAP2, ANKK1, DAT1 on attention deficit hyperactivity disorder (ADHD) and to emphasize the importance of genetic architecture in the learning experience and the development of an individual since genes can negatively affect an individual's life. Another rationale for this study was the very well-known problem of accurately diagnosing ADHD because this is usually made through questionnaires or interviews with the patient suspected of having the disorder, which can lead to errors. The idea of genetic testing to identify the different polymorphisms of genes responsible for ADHD would make the diagnosis more accurate. As a result, we searched the databases for articles in which the authors reported the impact of the genes mentioned above. We identified a total of 12 relevant articles that were discussed throughout this article. We concluded that all the genes selected for this study were implicated in the manifestation of this disorder, only when a specific circumstance was met such as a specific ethnic group was tested, or a specific polymorphism was studied. KEYWORDS Attention Deficit Hyperactivity Disorder, genetics, SNAP25, BAIAP2, ANKK1, DAT1. INTRODUCTION Attention deficit hyperactivity disorder (ADHD) hereditary impact is estimated at about 76%, it was difficult to identify genes fundamental for the manifestation of ADHD. ADHD is a multifactorial disorder, in which many genes, all with limited effects, are thought to cause the disorder in the presence of adverse environmental conditions (1).