                                     !!!"     #       $ %     & ’()%**+,%-)". /0& ’()%**+,%-)!* 1%& 2 Research Article Proteins: Structure, Function and Bioinformatics DOI 10.1002/prot.24564 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as an ‘Accepted Article’, doi: 10.1002/prot.24564 © 2014 Wiley Periodicals, Inc. Received: Jan 13, 2014; Revised: Mar 14, 2014; Accepted: Mar 14, 2014