_____________________________________________________________________________________________________ *Corresponding author: E-mail: kayjaybal@yahoo.com; Asian Journal of Fisheries and Aquatic Research 12(6): 38-48, 2021; Article no.AJFAR.69446 ISSN: 2582-3760 Trace Metals in Selected Fish Species from Five Cowries Creek, Southwest Nigeria: Consumer Safety Assessment Kayode James Balogun 1* , Kazeem Oladeji Kareem 2 and Emmanuel Kolawole Ajani 2 1 Department of Biological Oceanography, Nigerian Institute for Oceanography and Marine Research, Lagos, Nigeria. 2 Department of Aquaculture and Fisheries Management, University of Ibadan, Ibadan, Nigeria. Authors’ contributions This work was carried out in collaboration among all authors. Author KJB designed the study, performed the statistical analysis, wrote the protocol and wrote the first draft of the manuscript. All authors managed the analyses of the study. Author KOK managed the literature searches. All authors read and approved the final manuscript. Article Information DOI: 10.9734/AJFAR/2021/v12i630252 Editor(s): (1) Dr. Matheus Ramalho de Lima, Federal University of South of Bahia, Brazil. Reviewers: (1) Mariana Rodrigues dos Santos, Universidade de São Paulo, Brazil. (2) Mohd Shaiful Azman Bin Abdul Rahim, Universiti Malaysia Kelantan, Malaysia. Complete Peer review History: http://www.sdiarticle4.com/review-history/69446 Received 10 April 2021 Accepted 17 June 2021 Published 22 June 2021 ABSTRACT This study aims to examine trace metals (Pb, Cd, Cr, Zn, and Cu) concentration in muscle tissues of four fish species from Five Cowries Creek and assess the safety risks posed by consuming these fish species. For this purpose, fish species such as Cynoglossus senegalensis, Mugil cephalus, Chrysichthys nigrodigitatus and Pseudotolithus typus were procured monthly from anglers in Five Cowries Creek, Lagos, from February to May, 2019. The fish muscle tissues were digested according to the international standards, and the trace metals were measured using an atomic absorption spectrophotometer (AAS). Results revealed that the ranking order of trace element concentrations followed this sequence: Pb > Cr > Zn > Cu > Cd. There were significant differences (P < 0.05) in Pb and Cr among the fish species. Consumer health risk was evaluated using non-carcinogenic and carcinogenic risk indices. The results showed that EDI and target hazard quotient (THQ) of Cr, Zn, Cu and Cd suggested that fish species consumption did not pose Original Research Article