https://www.alliedacademies.org/journal-primary-care-general-practice/ J Prim Care Gen Pract 2020 Volume 3 Issue 3 Research Article Introduction A pressure ulcer is a localized injury to the skin and/or underlying tissue usually over a bony prominence, because of pressure, or pressure in combination with shear and/or friction [1-3]. Pressure ulcer also known as bed sore, pressure sore and decubitus ulcer [4]. Prolonged pressure impede capillary and venous return thus limit the delivery of oxygen and nutrients to tissue resulted with Metabolic wastes accumulation causes local vasodilatation [5,6], which contributes to edema compresses small vessels and ischemia prone patients at risk for pressure ulcer development [7,8]. Each year thousands of patients die of it and millions suffering from it in USA alone [9-13]. The number of patient suffering from PU is a few as 7.3% in hospitals in Europe and as high as 23% in North America [14-17], and 15.5% Malaysia [18-21]. Study reports in Africa revealed comparable magnitudes of pressure ulcer. In Nigeria it ranged from 3.22% to 18.6 % [4, 22]; whereas in Ethiopian hospitals it ranges from 13.4% to 16.8 % [23, 24]. A multicenter study in Brazil, prevalence of PU was 16.9%. Of which 16.3% patients had more than three PU [25]. Based on anatomical location; Sacral 82.5%, trochanter 37.5%, calcaneus 27.5%, Lumbar 6.3% and elbow 3.7% were the most affected. Whereas Patients presented with stage I 30.3 %, stage II 32.9 %, stage III 22.8 % and IV 13.9 % [26]. Background: On average, 60,000 people die each year worldwide due to pressure ulcer related causes. Even though, few studies reported the prevalence of pressure ulcer in some part of Ethiopia, there is paucity of information on the other side. Objectives: To Assess prevalence of Pressure Ulcer and Associated Factors Among Hospitalized Adult Patients in Public Hospitals in Sidama Zone; South Nations Nationalities, and Peoples’ Regional State, Ethiopia, 2017. Methods: Institution based cross sectional study design was employed to assess pressure ulcer prevalence and associated factors in Sidama Zone from March13-April 12, 2017, On 356 subjects. Multistage sampling technique was employed to reach individual study subjects. Data was entered into EPI- data version 3.1 and was analyzed by using SPSS version 20 statistical software. Descriptive statistics, Bivariate and multivariate logistic regression were computed to assess statistical association using Odds Ratio. Signifcant of statistical association was assured or tested using 95% confdence interval and p value (<0.05). Results: A total of 56 Patients were Develop pressure ulcer from 356 admitted in Public Hospitals, with the prevalence rate of 15.7 %; from which 6 (1.7%), 34 (9.6%), and 16 (4.5%) were Medical Device Related Pressure Ulcers and Routine Pressure Ulcers .Patient who had No Position change by nurse were 4.53 times (95% CI: AOR, 4.346 (1.646 – 11.473; P= 0.003) more likely to develop Pressure ulcer than Participants who had position change. Patients who had Body mass index Less than 18.5 kg/m2 were 6.9 times (95% CI: AOR, 6.91 (1.307,36.554) more likely to develop pressure ulcers than Patients who had BMI in between 25-29.99kg/m2. Conclusion and Recommendation: The Overall prevalence of pressure ulcer on this study is high. Position change, Activity, mobility, moisture, Antimicrobial, and ant diabetic were signifcantly associated with the development of pressure ulcer; Sidama Hospitals should Perform Risk and comprehensive assessment for all patients as soon as possible after admission, Provision of training for Nurses on Manual handling techniques when positioning and transferring patients, and if ,health condition patients permit nurses should reposition patient every two hours. Abstract Keywords: Pressure ulcers, Risk factors, Prevalence, Sidama Zone. Accepted on August 18, 2020 Prevalence of Pressure Ulcer and Associated Factors Among Hospitalized Adult Patients in Public Hospitals Sidama Zone, South Nations, Nationalities, and Peoples’ Regional State, Ethiopia, 2017. *AAbiru Neme 1 *, Wadu Wolancho 1 , Gugsa Nemera 1 , Yosef Yohanes 2 1 Jimma University, Institute of Health, School of Nursing, Ethiopia 2 Hawassa Health Sciences College, South Nations Nationalities, and Peoples’ Regional, Ethiopia 3