What’s Happening to Our Body after Drinking Coke ? -- The Characteristic of the Blood Pressure Wave in Radial Artery Sheng-Chieh Huang, Yung-Pin Lee, Min-Hua Hsieh, Hui-Min Wang, Mark C. Hou M.D.,TCM.D. , Shih-Chun Chao M.D.,TCM.D. , Cheng-Lung Tseng, Wei-Ta Hsiao, Chung-Hung Hong, Kai-Yu Shao, Shi-Han Luo, Wei-Chun Chiu and Wei-Yu Chen sense/tcm SOC Lab, Dept. of Electrical Engineering National Chiao Tung University Hsinchu, Taiwan, ROC E-mail: schuang@cn.nctu.edu.tw Abstract —Previous literature has suggested that psychological state may be changed via drinking coke; however, studies empirically documenting the link between coke and blood pressure wave (BPW) are scant. Therefore, the current article attempts to explore how coke intervene the mental condition with the assessment of pulse signal recordings.The quantitative analysis of the data was conducted through SAS, EXCEL and MATLAB package software in order to find a specific pattern of pulse spectrum. Results of this study showed the high frequency of heart rate variability increased from 34.83 to 43.83, and that of beat-to-beat pulse variability was enhanced from 7.67 to 35.5. The value of beat-to beat pulse variability in time-domain also went up. The relationship between sd1 and sd2 of RRI and HRV are positively correlated. Keywords - Blood pressure wave (BPW) ; spectrum analysis; Sphygmogram; Traditional Chinese medicine (TCM) I. INTRODUCTION Ttraditional medicine (TM), which refers to various systems of indigenous medicine, such as Chinese medicine, Arabic Unani medicine, and Indian Ayurveda, is quite popular on earth. The World Health Organization (WHO) defines TM as follows: “Traditional medicine includes diverse health practices, approaches, knowledge and beliefs incorporating plant, animal, and/or mineral based medicines, spiritual therapies, manual techniques and exercises applied singularly or in combination to maintain well-being, as well as to treat, diagnose or prevent illness [1].” Besides, Complementary and alternative medicine (CAM) has a close but slightly different definition, and is described by the WHO as follows: “The terms complementary and alternative (and sometimes also “non-conventional” or “parallel”) are used to refer to a broad set of health care practices that are not part of a country’s own tradition, or not integrated into its dominant health care system [1]. ” Although the definitions of both terms differ, they are often used together as TM/CAM. Of the many types of TM/CAM, traditional Chinese medicine (TCM), based on the unique philosophical foundation, complete theoretical system and great therapeutic facilities, has gained in popularity as an alternative to Western medicine over the past few decades. There has been a tremendous wave of interest in how this traditional medicine with six-thousand-year history works. Therefore, the number of publications on Chinese medicine and on related issues has increased markedly, particularly in Australia, Britain, Germany, and the United States. The Pulse-taking of radial artery in both hands is widely used among Traditional Chinese Medicine (TCM) diagnosis procedure. In order to get more understandings of the bulleye, the study of the blood pressure wave, or sphygmology, has undergone various shifts over the years. From the perspective of contemporary science, this ancient assessment is studied with the characteristics of the blood pressure wave collected with transducers. However, due to the intangible attribute of Qi, meridians, and other fundamental elements in human body presented in the TCM paradigm, it has been accessed in various approaches. Resonnance theory, the spectrum analysis of BPW, is one of the scientific model explaining how pulse provides vital information of organs’ condition. Wang et al. stated that some harmonic wave of BPW is correlated with another specific organ. For example, the first harmonic represents liver system, the second one implies the function of kidney system, while the third Fourier component is the indicator of spleen system, etc. Therefore, the heart modulates the harmonic components in order to arrange different amount of blood flow into organs [2]. Research on music has suggested that it would likely affect our nervous system, thus causing any change on the cardiovascular system [3]-[7]. However, research which has empirically documented the link between heart rate variability (HRV) or beat- to-beat pulse variability (BPV) and coke is scant. Therefore, the purpose of this article attempts to 2011 Second International Conference on Innovations in Bio-inspired Computing and Applications 978-0-7695-4606-3/11 $26.00 © 2011 IEEE DOI 10.1109/IBICA.2011.15 41 2011 Second International Conference on Innovations in Bio-inspired Computing and Applications 978-0-7695-4606-3/11 $26.00 © 2011 IEEE DOI 10.1109/IBICA.2011.15 41