Open Journal of Urology, 2018, 8, 267-274 http://www.scirp.org/journal/oju ISSN Online: 2160-5629 ISSN Print: 2160-5440 DOI: 10.4236/oju.2018.89030 Sep. 5, 2018 267 Open Journal of Urology Post-Obstructive Diuresis: Physiopathology, Diagnosis and Management after Urological Treatment of Obstructive Renal Failure Sumba Harrison 1,2* , Abdelouahed Lasri 1,2 , Youness Jabbour 1,2 , Amine Slaoui 1,2 , Jacquet Djamal 3 , Tariq Karmouni 1,2 , Kadir El Khader 1,2 , Abdelatif Koutani 1,2 , Ahmed Ibn Attiya Andaloussi 1,2 1 Department of Urology “B”, Ibn Sina University Hospital, Rabat, Morocco 2 Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco 3 Department of Uro-Andrology, Faculty of Health Sciences, Cotonou, Benin Abstract Obstructive acute renal failure is both a medical and a surgical emergency. The first treatment modality is urological by relief of obstruction. Post-obstructive diuresis is an abnormal condition of prolonged polyuria, involving both ex- cessive solute and water loss, after acute drainage of obstructed urinary tract system. Physiopathology mechanisms are multiples. In most patients, diuresis will resolve once the kidneys normalize the volume and solute status and ho- meostasis is achieved. Post-obstructive diuresis can occur in up to 50% of pa- tients with substantial urinary tract obstruction and can be life-threatening if it becomes pathologic. It can be detected by hourly monitoring of diuresis. Medical treatment of post-obstructive diuresis consists of oral or intravenous fluids adjusted to the findings of clinical examination, diuresis (volume and electrolytes) and close monitoring of patient. Fluid compensation should be tapered off over several days. Patients at high risk of post-obstructive diuresis should be identified and appropriately monitored. Keywords Post-Obstructive Diuresis, Acute Renal Failure, Water and Electrolyte Compensation 1. Introduction Post-obstructive diuresis (POD) is defined as the condition of prolonged urine production of at least 200 ml for at least two consecutive hours immediately fol- lowing the relief of urinary retention or similar obstructive uropathy. It may also be How to cite this paper: Harrison, S., Lasri, A., Jabbour, Y., Slaoui, A., Djamal, J., Kar- mouni, T., El Khader, K., Koutani, A. and Andaloussi, A.I.A. (2018) Post-Obstructive Diuresis: Physiopathology, Diagnosis and Management after Urological Treatment of Obstructive Renal Failure. Open Journal of Urology, 8, 267-274. https://doi.org/10.4236/oju.2018.89030 Received: July 30, 2018 Accepted: September 2, 2018 Published: September 5, 2018 Copyright © 2018 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access